FIGURE

Fig. 5

ID
ZDB-FIG-140311-33
Publication
Gebruers et al., 2013 - A Phenotypic Screen in Zebrafish Identifies a Novel Small-Molecule Inducer of Ectopic Tail Formation Suggestive of Alterations in Non-Canonical Wnt/PCP Signaling
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Fig. 5

pCAME induces convergence and extension defects.

(A) and (B) flh expression; (C) and (D) ntl; (E) and (F) papc; (G) and (H) myoD. All embryos were treated at 2-4 cell stages with 14 or 28 μM pCAME and fixed at 1 somite stage. Dorsal view. Expression domains of compound-treated fish are altered as would be predicted for CE defects. Embryos have a broader and shorter notochord and impaired convergence and extension of the para-axial mesoderm and the somites.

Expression Data

Expression Detail
Antibody Labeling
Phenotype Data

Phenotype Detail
Acknowledgments
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