FIGURE

Fig. 3

ID
ZDB-FIG-130808-2
Publication
Dagliyan et al., 2013 - Rational design of a ligand-controlled protein conformational switch
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Fig. 3

Testing uniRapR in different kinases and effects of Src activation in HeLa cells. Immunoprecipitation, in vitro FAK (A), and p38 (B) assays were performed similarly as for Src kinase. (C) Change in cell area of HeLa cells expressing Src (YF)-uniRapR (n = 8/8 cells) or Src (YF/KD)-uniRapR (n = 8/8 cells). (D) HeLa cells expressing Src-uniRapR (YF)-cerulean demonstrate spreading after the addition of rapamycin.

Expression Data

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Antibody Labeling
Phenotype Data

Phenotype Detail
Acknowledgments
This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ Proc. Natl. Acad. Sci. USA