Fig. 3

Koltowska et al., 2013 - Ssrp1a controls organogenesis by promoting cell cycle progression and RNA synthesis
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Fig. 3

Ssrp1a promotes cell cycle progression. (A-C) BrdU incorporation is reduced in ssrp1as819 mutant livers from 38 hpf onwards (outlined). Error bars represent s.d. (D-G) Transgenic cecyil expression marks G1 phase cells in red and S/G2/M phase cells in green. (H) Quantification of hepatoblast proliferation shows a reversed distribution in controls and ssrp1as819 mutants at 48 hpf. (I) FACS analysis of 42-44 hpf foregut endoderm shows an increase of cells in S phase and a decrease of those in G1 phase in ssrp1as819 mutants. A-B′,D-G are confocal projections of ventral views; all anterior to the top. *P<0.05, ***P<0.0005, determined by unpaired Student’s t-test.

Expression Data
Anatomical Term:
Stage Range: Prim-25 to High-pec

Expression Detail
Antibody Labeling
Phenotype Data
Observed In:
Stage Range: Prim-25 to High-pec

Phenotype Detail
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