FIGURE

Fig. 5

ID
ZDB-FIG-121220-12
Publication
Zhao et al., 2012 - Dopaminergic neuronal loss and dopamine-dependent locomotor defects in fbxo7-deficient zebrafish
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Fig. 5

zFbxo7 knock down results in locomotor defects, which are improved by apomorphine.

The movements of WT zebrafish, ATG-MO-Mild and SP-MO-Mild morphants were recorded during three cycles of 10-minutes light/10-minutes darkness (periods of darkness are shown in grey). Compared with WT, morphants showed significantly decreased velocity in both light and dark phases (P<0.01, panel A), which were significantly improved by treatment with apomorphine (P<0.01 in the dark phase, panels B and C). Dom: domperidone. Apo: apomorphine.

Expression Data

Expression Detail
Antibody Labeling
Phenotype Data
Fish:
Condition:
Knockdown Reagents:
Observed In:
Stage: Day 4

Phenotype Detail
Acknowledgments
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