FIGURE

Fig. 3

ID
ZDB-FIG-121212-37
Publication
Gyda et al., 2012 - The tumor suppressor gene retinoblastoma-1 is required for retinotectal development and visual function in zebrafish
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Fig. 3

rb1 mRNA overexpression rescues optic nerve hypoplasia in rb1te226 mutants.

(A-B) Optic nerves of uninjected wild type (A) and rb1te226a; ath5:gfp+/- embryos (B) at 48 hpf. (C-D) Optic nerves of rb1te226a; ath5:gfp+/- embryos injected with 10 pg of wild type rb1 (C) or rb1te226a (D) mRNA. Dorsal view of maximum intensity projection of confocal z-stacks. (E) Mean optic nerve diameter, measured at dashed rectangle in (A). Error bars denote SEM. *p<0.001, #p<0.01; one-way ANOVA with brackets indicating compared groups. N optic nerves shown at base of bar graphs. Anterior to the top of panel, scale bar = 50 μm.

Expression Data

Expression Detail
Antibody Labeling
Phenotype Data

Phenotype Detail
Acknowledgments
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