FIGURE

Fig. S4

ID
ZDB-FIG-120918-5
Publication
Sorrells et al., 2012 - Ccdc94 Protects Cells from Ionizing Radiation by Inhibiting the Expression of p53
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Fig. S4

Loss of ccdc94 compromises the anti-apoptotic function of Bcl-2. Wild-type (wt, derived from crossing wild-type parents) or rs7 mutant embryos (derived from crossing rs7 heterozygous parents) were injected at the one-cell stage of development with the indicated amounts of mRNA encoding zbcl-2, zbcl-xL, or egfp as a control (cntl). Embryos were then irradiated at 24 hpf with 8 Gy IR and analyzed three hours later by immunofluorescence to detect activated Caspase-3. Mutants were genotyped as in Figure 2C–2D. Representative data from three independent experiments is shown.

Expression Data

Expression Detail
Antibody Labeling
Phenotype Data

Phenotype Detail
Acknowledgments
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