FIGURE

Fig. S2

ID
ZDB-FIG-120126-73
Publication
Nguyen et al., 2012 - An inducible krasV12 transgenic zebrafish model for liver tumorigenesis and chemical drug screening
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Fig. S2

Activation of both ERK and AKT pathways in advanced liver cancer of krasV12 transgenic fish. Driver-effector fish induced with mifepristone (RU486) for more than 8 weeks developed hepatoblastoma (HB) and ascites in mixed HCC. (A) Immunohistochemistry for PERK1/ 2 and P-AKT showing positive nuclear and cytoplasmic staining of both P-ERK1/2 and PAKT proteins in HB (dotted area). (B) Ascites and cyst fluid in mixed HCC also displaying strong expression of P-ERK1/2 and P-AKT protein.

Expression Data

Expression Detail
Antibody Labeling
Phenotype Data

Phenotype Detail
Acknowledgments
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