ZFIN Figure: Rooryck et al., 2011, Fig. 4

ZFIN ID: ZDB-FIG-110422-7

ZFIN ID: ZDB-FIG-110422-7

Rooryck et al., 2011 - Mutations in lectin complement pathway genes COLEC11 and MASP1 cause 3MC syndrome. Nature Genetics 43(3):197-203 Full text @ Nat. Genet.

ADDITIONAL FIGURES

PHENOTYPE:

Fish:	WT + MO1-masp1 + MO2-masp1 WT + MO1-colec11 + MO1-masp1 + MO2-colec11 + MO2-masp1
Knockdown Reagents:	MO1-colec11 MO1-masp1 MO2-colec11 MO2-masp1
Observed In:	ceratohyal cartilage embryonic viscerocranium morphogenesis ethmoid cartilage Meckel's cartilage palatoquadrate cartilage pigment cell
Stage:	Day 5

Fig. 4 ZFIN is incorporating published figure images and captions as part of an ongoing project. Figures from some publications have not yet been curated, or are not available for display because of copyright restrictions.

Gene Expression Details No data available

Antibody Labeling Details No data available

Phenotype Details

Fish	Conditions	Stage	Phenotype
WT + MO1-colec11 + MO1-masp1 + MO2-colec11 + MO2-masp1	standard conditions	Day 5	ceratohyal cartilage malformed, abnormal
		Day 5	embryonic viscerocranium morphogenesis process quality, abnormal
		Day 5	ethmoid cartilage malformed, abnormal
		Day 5	Meckel's cartilage decreased length, abnormal
		Day 5	palatoquadrate cartilage decreased length, abnormal
WT + MO1-masp1 + MO2-masp1	standard conditions	Day 5	ceratohyal cartilage malformed, abnormal
		Day 5	embryonic viscerocranium morphogenesis process quality, abnormal
		Day 5	Meckel's cartilage decreased length, abnormal
		Day 5	palatoquadrate cartilage decreased length, abnormal
		Day 5	pigment cell spatial pattern, abnormal

Full text @ Nat. Genet.