ZFIN Figure: Hyvarinen et al., 2010, Fig. 4

ZFIN ID: ZDB-FIG-110131-9

ZFIN ID: ZDB-FIG-110131-9

Hyvarinen et al., 2010 - Deficiency of a transmembrane prolyl 4-hydroxylase in the zebrafish leads to basement membrane defects and compromised kidney function. The Journal of biological chemistry 285(53):42023-42032 Full text @ J. Biol. Chem.

ADDITIONAL FIGURES

PHENOTYPE:

Fish:	WT + MO1-p4htmb
Knockdown Reagent:	MO1-p4htmb
Observed In:	eye lens lens capsule basement membrane lens epithelium nucleus lens fiber cell development retina
Stage:	Day 4

Fig. 4 ZFIN is incorporating published figure images and captions as part of an ongoing project. Figures from some publications have not yet been curated, or are not available for display because of copyright restrictions.

Gene Expression Details No data available

Antibody Labeling Details No data available

Phenotype Details

Fish	Conditions	Stage	Phenotype
WT + MO1-p4htmb	standard conditions	Day 4	eye decreased size, abnormal
		Day 4	lens capsule basement membrane broken, abnormal
		Day 4	lens capsule basement membrane decreased thickness, abnormal
		Day 4	lens epithelium nucleus mislocalised, abnormal
		Day 4	lens fiber cell development disrupted, abnormal
		Day 4	lens opaque, abnormal
		Day 4	retina disorganized, abnormal

Full text @ J. Biol. Chem.