ZFIN ID: ZDB-FIG-110131-9
Hyvarinen et al., 2010 - Deficiency of a transmembrane prolyl 4-hydroxylase in the zebrafish leads to basement membrane defects and compromised kidney function. The Journal of biological chemistry   285(53):42023-42032 Full text @ J. Biol. Chem.
Knockdown Reagent:
Observed In:
Stage: Day 4

Fig. 4 ZFIN is incorporating published figure images and captions as part of an ongoing project. Figures from some publications have not yet been curated, or are not available for display because of copyright restrictions.

Gene Expression Details No data available
Antibody Labeling Details No data available
Phenotype Details
Fish Conditions Stage Phenotype
WT + MO1-p4htmb standard conditions Day 4 eye decreased size, abnormal
Day 4 lens capsule basement membrane broken, abnormal
Day 4 lens capsule basement membrane decreased thickness, abnormal
Day 4 lens epithelium nucleus mislocalised, abnormal
Day 4 lens fiber cell development disrupted, abnormal
Day 4 lens opaque, abnormal
Day 4 retina disorganized, abnormal
Full text @ J. Biol. Chem.