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Research
General Information
ZIRC
ZFIN ID: ZDB-FIG-100524-2
van Rooijen et al., 2010 - von Hippel-Lindau tumor suppressor mutants faithfully model pathological hypoxia-driven angiogenesis and vascular retinopathies in zebrafish. Disease models & mechanisms   3(5-6):343-353 Full text @ Dis. Model. Mech.
ADDITIONAL FIGURES
EXPRESSION / LABELING:
Genes:
Fish:
Anatomical Terms:
Stage Range: Long-pec to Days 7-13
PHENOTYPE:
Fish:
Observed In:
Stage Range: Long-pec to Days 7-13

Fig. 2 ZFIN is incorporating published figure images and captions as part of an ongoing project. Figures from some publications have not yet been curated, or are not available for display because of copyright restrictions.

Gene Expression Details
Gene Antibody Fish Conditions Stage Anatomy Assay
EGFP s843Tg standard conditions Long-pec cranial vasculature IFL
Long-pec trunk vasculature IFL
Protruding-mouth cranial vasculature IFL
Protruding-mouth trunk vasculature IFL
Day 5 cranial vasculature IFL
Day 5 trunk vasculature IFL
s916Tg; y1Tg standard conditions Days 7-13 lymph vasculature IFL
Days 7-13 trunk vasculature IFL
vhlhu2081/+; vhlhu2117/+; s843Tg standard conditions Long-pec cranial vasculature IFL
Long-pec trunk vasculature IFL
Protruding-mouth cranial vasculature IFL
Protruding-mouth trunk vasculature IFL
Day 5 cranial vasculature IFL
Day 5 trunk vasculature IFL
vhlhu2081/+; vhlhu2117/+; s916Tg; y1Tg standard conditions Days 7-13 lymph vasculature IFL
Days 7-13 trunk vasculature IFL
mCherry s916Tg; y1Tg standard conditions Days 7-13 trunk vasculature IFL
vhlhu2081/+; vhlhu2117/+; s916Tg; y1Tg standard conditions Days 7-13 trunk vasculature IFL
Antibody Labeling Details No data available
Phenotype Details
Fish Conditions Stage Phenotype
vhlhu2081/+; vhlhu2117/+; s843Tg standard conditions Long-pec angiogenesis increased occurrence, abnormal
Long-pec cranial blood vessel increased amount, abnormal
Protruding-mouth blood vessel increased diameter, abnormal
Protruding-mouth cranial blood vessel increased amount, abnormal
Protruding-mouth intersegmental vessel branched, abnormal
Protruding-mouth sprouting angiogenesis increased occurrence, abnormal
Day 5 angiogenesis increased occurrence, abnormal
Day 5 cranial blood vessel increased amount, abnormal
Day 5 intersegmental vessel branched, abnormal
Day 5 trunk vasculature blood vessel increased amount, abnormal
vhlhu2081/+; vhlhu2117/+; s916Tg; y1Tg standard conditions Days 7-13 lymphangiogenesis process quality, normal
Full text @ Dis. Model. Mech.