FIGURE

Fig. 8

ID

ZDB-FIG-090519-6

Publication

Tokumoto et al., 1995 - Molecular heterogeneity among primary motoneurons and within myotomes revealed by the differential mRNA expression of novel islet-1 homologs in embryonic zebrafish

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Fig. 8

zfIsl-2 mRNA expression in the 24-hr spt mutant embryos. A photomontaged lateral view. Deficient cell migration during epiboly results in defective somites in the middle body trunk and the abnormal accumulation of cells at the end of the tail (T) in the spt mutant embryo. The embryo shown here has 10 apparently regular somites. The somite borders are indicated by lines. zfIsl-2 mRNA was not expressed in the ventral spinal cord caudal to the last 5 somites and expressed only in single or pairs of ventral cells (arrows) at the midsegments in the region surrounded by the anterior 5 of the 10 regular somites. In contrast, in the more anterior region where the somatic structure was severely disturbed, the zfIsl-2-positive ventral cells (arrowheads) significantly decreased in number per one segment length (0.5 in this mutant embryo compared to ∼1.5 in the normal embryos). S, spinal cord; N, notochord. Anterior, left; dorsal, up. Bar, 50 μm.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

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Reprinted from Developmental Biology, 171, Tokumoto, M., Gong, Z.Y., Tsubokawa, T., Hew, C.L., Uyemura, K., Hotta, Y., and Okamoto, H., Molecular heterogeneity among primary motoneurons and within myotomes revealed by the differential mRNA expression of novel islet-1 homologs in embryonic zebrafish, 578-589, Copyright (1995) with permission from Elsevier. Full text @ Dev. Biol.