FIGURE
Fig. 1
- ID
- ZDB-FIG-090506-31
- Publication
- Waxman et al., 2009 - Increased Hox activity mimics the teratogenic effects of excess retinoic acid signaling
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Fig. 1
Increased RA signaling and Hox activity cause similar body axis phenotypes. A: Wild-type embryo. B: Low RA causes reduction of anterior head. C: High RA causes loss of anterior head and tail truncation. D, E: Injection of 150 pg of hoxb5b mRNA causes reduction or loss of anterior head. F: Injection of 30 pg of vp-hoxb5b mRNA causes loss of anterior head. G: Injection of 60 pg of vp-hoxb5b mRNA causes loss of anterior head and tail truncation. All images are at 48 hpf with anterior to the left. Arrows indicate reduced head and eyes. Arrowheads indicate loss of anterior head. Scale bar = 100 μM. |
Expression Data
Expression Detail
Antibody Labeling
Phenotype Data
Phenotype Detail
Acknowledgments
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