FIGURE

Fig. 5

ID

ZDB-FIG-080605-30

Publication

Quint et al., 2002 - Bone patterning is altered in the regenerating zebrafish caudal fin after ectopic expression of sonic hedgehog and bmp2b or exposure to cyclopamine

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Fig. 5

BrdUrd-incorporation in fins treated with cyclopamine or solanidine. After 1 day of treatment (initiated at 2 dpa) with either solanidine (A) or cyclopamine (B), proliferating cells were identified in the epidermis (solid arrows) and mesenchyme (arrowheads) in the region of new bone matrix secretion. By day 3, BrdUrd-labeled cells were still found in the epidermal layers of both control and cyclopamine-treated fins (C, D, solid arrows) and in the mesenchyme of solanidine-treated fins (C, arrowheads), but not in the mesenchyme of cyclopamine-treated fins (D). Dotted lines mark the level of amputation. (Bar = 50 μm.)

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ Proc. Natl. Acad. Sci. USA