FIGURE

Fig. 3

ID

ZDB-FIG-080514-48

Publication

Willot et al., 2002 - Cooperative action of ADMP- and BMP-mediated pathways in regulating cell fates in the zebrafish gastrula

Other Figures

All Figure Page

Back to All Figure Page

Fig. 3

admp overexpression causes the loss of dorsal fates. wt embryos were injected at the one-cell stage with admp RNA (600 pg) and compared to uninjected siblings (control). (A–D) Live embryos at 1 day of development. (E, F) Flat mounts of embryos stained at the one-to three-somite stage with myoD and pax2.1 in dark blue, hgg1, krox20, and ntl in red; anterior to the left. (A) Uninjected embryo. (B–D) admp-injected embryos. (B) Class 1 phenotype. (C) Class 2 phenotype. (D) Class 3 phenotype. (B, C) Arrows indicate the posterior limit of the truncated notochord. (E) Uninjected embryo. (F) admp-injected embryo; notochord defects and fusion of myoD expression domains at the midline are indicated (arrows).

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image.

Reprinted from Developmental Biology, 241(1), Willot, V., Mathieu, J., Lu, Y., Schmid, B., Sidi, S., Yan, Y.-L., Postlethwait, J.H., Mullins, M., Rosa, F., and Peyriéras, N., Cooperative action of ADMP- and BMP-mediated pathways in regulating cell fates in the zebrafish gastrula, 59-78, Copyright (2002) with permission from Elsevier. Full text @ Dev. Biol.