FIGURE

Fig. 4

ID

ZDB-FIG-080418-9

Publication

Griffin et al., 2003 - Interplay between FGF, one-eyed pinhead, and T-box transcription factors during zebrafish posterior development

Other Figures

All Figure Page

Back to All Figure Page

Fig. 4

Spt and ntl mutant embryos are hypersensitive to FGFR inhibition. (A–C) Embryos from ntl/+ adults. (A) Myosin staining in an untreated ntl mutant embryo. (B) Presumptive ntl mutant embryo treated with 4 μM SU5402; myosin staining is dramatically reduced relative to (A) and (C) ntl +/+ and +/- embryos treated with 4 μM SU5402. (D–F) Embryos obtained from spt/+ adults. (D) Untreated spt mutant embryos have patchy myosin staining in the trunk and segmented staining in the tail. (E) spt mutant embryos treated with 7 μM SU5402 are almost devoid of myosin staining, whereas (F) spt +/+ and +/- embryos treated with 7 μM SU5402 appear similar to untreated wild-type embryos.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image.

Reprinted from Developmental Biology, 264(2), Griffin, K.J. and Kimelman, D., Interplay between FGF, one-eyed pinhead, and T-box transcription factors during zebrafish posterior development, 456-466, Copyright (2003) with permission from Elsevier. Full text @ Dev. Biol.