CRISPR

CRISPR1-exosc8

ID
ZDB-CRISPR-210128-1
Name
CRISPR1-exosc8
Previous Names
None
Target
Sequence
5' - GGGATATTCAAGAGGCTCTG - 3'
Disclaimer
Although ZFIN verifies reagent sequence data, we recommend that you conduct independent sequence analysis before ordering any reagent.
Note
The first two "G"s were added.
Genome Resources
None
Target Location
Constructs
No data available
Genomic Features
Genomic Feature Affected Genomic Regions
cu201 exosc8
Expression
Gene expression in Wild Types + CRISPR1-exosc8
No data available
Phenotype
Phenotype resulting from CRISPR1-exosc8
No data available
Phenotype of all Fish created by or utilizing CRISPR1-exosc8
Phenotype Fish Conditions Figures
skeletal muscle cell disorganized, abnormal exosc8cu201/cu201 standard conditions Figure S4. with image from Müller et al., 2020
eye decreased size, abnormal exosc8cu201/cu201 standard conditions Figure 1. with image from Müller et al., 2020
ceratohyal bone position, abnormal exosc8cu201/cu201 standard conditions Figure 7. with image from Müller et al., 2020
head decreased size, abnormal exosc8cu201/cu201 standard conditions Figure 1. with image from Müller et al., 2020
whole organism tp53 expression increased amount, abnormal exosc8cu201/cu201 standard conditions Fig. 2 from Müller et al., 2020
midbrain decreased size, abnormal exosc8cu201/cu201 standard conditions Figure 3. with image from Müller et al., 2020
whole organism cbln8 expression decreased amount, abnormal exosc8cu201/cu201 standard conditions Fig. 2 from Müller et al., 2020
ceratohyal bone decreased length, abnormal exosc8cu201/cu201 standard conditions Figure 7. with image from Müller et al., 2020
whole organism otx2b expression decreased amount, abnormal exosc8cu201/cu201 standard conditions Fig. 2 from Müller et al., 2020
head apoptotic process increased occurrence, abnormal exosc8cu201/cu201 standard conditions Figure 4. with image from Müller et al., 2020
motor neuron axon decreased branchiness, abnormal exosc8cu201/cu201 standard conditions Figure S3. with image from Müller et al., 2020
swim bladder uninflated, abnormal exosc8cu201/cu201 standard conditions Figure 1. with image from Müller et al., 2020
caudal fin decreased thickness, abnormal exosc8cu201/cu201 standard conditions Figure S4. with image from Müller et al., 2020
cerebellum decreased size, abnormal exosc8cu201/cu201 standard conditions Figure 3. with image from Müller et al., 2020
Citations