CRISPR

CRISPR1-ppargc1a

ID

ZDB-CRISPR-200519-2

Name

CRISPR1-ppargc1a

Previous Names

None

Target

ppargc1a (1)

Sequence

5' - GGAAAATGAGGCCAACTTGC - 3'

Disclaimer

Although ZFIN verifies reagent sequence data, we recommend that you conduct independent sequence analysis before ordering any reagent.

Note

None

Genome Resources

None

Target Location

Constructs

No data available

Genomic Features

Genomic Feature	Affected Genomic Regions
bns176	ppargc1a

Expression

Gene expression in Wild Types + CRISPR1-ppargc1a

No data available

Phenotype

Phenotype resulting from CRISPR1-ppargc1a

No data available

Phenotype of all Fish created by or utilizing CRISPR1-ppargc1a

Phenotype	Fish	Conditions	Figures
cardiac muscle cell proliferation increased occurrence, abnormal	ppargc1a^{bns176/bns176}	cryoablation: cardiac ventricle	Fig. 2 from Fukuda et al., 2020
coronary artery endothelial cell atp5pf expression decreased amount, abnormal	ppargc1a^{bns176/bns176}; hu5333Tg	control	Fig. 1 from Marín-Juez et al., 2019
coronary artery endothelial cell apln expression increased amount, abnormal	ppargc1a^{bns176/bns176}; hu5333Tg	control	Fig. 1 from Marín-Juez et al., 2019
coronary artery endothelial cell ppargc1a expression decreased amount, abnormal	ppargc1a^{bns176/bns176}; hu5333Tg	cryoablation: heart	Fig. 1 from Marín-Juez et al., 2019
coronary artery endothelial cell atp5pf expression decreased amount, abnormal	ppargc1a^{bns176/bns176}; hu5333Tg	cryoablation: heart	Fig. 1 from Marín-Juez et al., 2019
coronary artery endothelial cell apln expression increased amount, abnormal	ppargc1a^{bns176/bns176}; hu5333Tg	cryoablation: heart	Fig. 1 from Marín-Juez et al., 2019
regenerating tissue cell population proliferation increased occurrence, abnormal	ppargc1a^{bns176/bns176}; hu5333Tg	cryoablation: heart	Fig. 1 from Marín-Juez et al., 2019
blood vessel endothelial cell cell population proliferation increased occurrence, abnormal	ppargc1a^{bns176/bns176}; hu5333Tg	cryoablation: heart	Fig. 1 from Marín-Juez et al., 2019
coronary artery endothelial cell ppargc1a expression decreased amount, abnormal	ppargc1a^{bns176/bns176}; hu5333Tg	control	Fig. 1 from Marín-Juez et al., 2019
coronary artery endothelial cell ndufb5 expression decreased amount, abnormal	ppargc1a^{bns176/bns176}; hu5333Tg	cryoablation: heart	Fig. 1 from Marín-Juez et al., 2019
coronary artery endothelial cell ndufb5 expression decreased amount, abnormal	ppargc1a^{bns176/bns176}; hu5333Tg	control	Fig. 1 from Marín-Juez et al., 2019

Citations