CRISPR

CRISPR1-vangl2

ID

ZDB-CRISPR-150730-2

Name

CRISPR1-vangl2

Previous Names

vangl2 Exon2 CRISPR (1)

Target

vangl2 (1)

Sequence

5' - GGATAACGAGTCGCAGTACT - 3'

Disclaimer

Although ZFIN verifies reagent sequence data, we recommend that you conduct independent sequence analysis before ordering any reagent.

Note

None

Genome Resources

None

Target Location

Constructs

No data available

Genomic Features

Genomic Feature	Affected Genomic Regions
hsc170Tg	vangl2

Expression

Gene expression in Wild Types + CRISPR1-vangl2

No data available

Phenotype

Phenotype resulting from CRISPR1-vangl2

No data available

Phenotype of all Fish created by or utilizing CRISPR1-vangl2

Phenotype	Fish	Conditions	Figures
whole organism anterior-posterior axis decreased length, abnormal	vangl2^{hsc170Tg/hsc170Tg} (TU)	standard conditions	Fig. 1 from Jussila et al., 2022
forebrain ventricle Ab1-RF labeling increased amount, abnormal	vangl2^{hsc170Tg/hsc170Tg}; hsc105bTg/+; hsc185Tg/+ (TU)	standard conditions	Fig. 8 from Jussila et al., 2022
hindbrain ependymal cell lacks parts or has fewer parts of type ependymal cell motile cilium, abnormal	vangl2^{hsc170Tg/hsc170Tg}; hsc105bTg/+; hsc185Tg/+ (TU)	standard conditions	Fig. 7 from Jussila et al., 2022
fourth ventricle Ab1-RF labeling increased amount, abnormal	vangl2^{hsc170Tg/hsc170Tg}; hsc105bTg/+; hsc185Tg/+ (TU)	standard conditions	Fig. 8 from Jussila et al., 2022
whole organism anterior-posterior axis increased curvature, abnormal	vangl2^{hsc170Tg/hsc170Tg}; hsc105bTg/+; hsc185Tg/+ (TU)	standard conditions	Fig. 6 from Jussila et al., 2022
floor plate ciliary basal body positional polarity, abnormal	vangl2^{hsc170Tg/hsc170Tg}; hsc105bTg/+; hsc185Tg/+ (TU)	standard conditions	Fig. 5 from Jussila et al., 2022
vertebral column rotational curvature, abnormal	vangl2^{hsc170Tg/hsc170Tg}; hsc105bTg/+; hsc185Tg/+ (TU)	standard conditions	Fig. 6 from Jussila et al., 2022
post-vent region curved dorsal, abnormal	vangl2^{hsc170Tg/hsc170Tg}; hsc105bTg/+; hsc185Tg/+ (TU)	standard conditions	Fig. 6 from Jussila et al., 2022
Reissner's fiber malformed, abnormal	vangl2^{hsc170Tg/hsc170Tg}; hsc105bTg/+; hsc185Tg/+ (TU)	standard conditions	Fig. 8 from Jussila et al., 2022
vertebral column increased curvature, abnormal	vangl2^{hsc170Tg/hsc170Tg}; hsc105bTg/+; hsc185Tg/+ (TU)	standard conditions	Fig. 6 from Jussila et al., 2022

Citations