FIGURE SUMMARY
Title

C2orf71a/pcare1 is important for photoreceptor outer segment morphogenesis and visual function in zebrafish

Authors
Corral-Serrano, J.C., Messchaert, M., Dona, M., Peters, T.A., Kamminga, L.M., van Wijk, E., Collin, R.W.J.
Source
Full text @ Sci. Rep.
Fig. 3

Pcare1rmc100/rmc100 zebrafish show aberrant photoreceptor morphology. (A) Analysis of the morphology of the pcare1rmc100/rmc100 zebrafish larval retina (5 dpf) using boron-dipyrromethene (BODIPY) revealed disorganization of photoreceptor outer segments as compared to those of strain- and age-matched wild-type larvae (arrows). (B) Siblings of adult zebrafish without (wild-type) or containing (pcare1rmc100/rmc100) the 29 bp deletion in pcare1 were sectioned and stained with antibodies against F-actin (red), Rhodopsin (green) or, in (C) GNAT2 (green). Arrows indicate normal outer segments in control fish and dysmorphic outer segments in mutant fish. Nuclei were stained with DAPI.
Acknowledgments
This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ Sci. Rep.
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