ZFIN Image: Corral-Serrano et al., 2018, Fig. 3

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Figure Caption

Fig. 3

Pcare1^{rmc100/rmc100} zebrafish show aberrant photoreceptor morphology. (A) Analysis of the morphology of the pcare1^{rmc100/rmc100} zebrafish larval retina (5 dpf) using boron-dipyrromethene (BODIPY) revealed disorganization of photoreceptor outer segments as compared to those of strain- and age-matched wild-type larvae (arrows). (B) Siblings of adult zebrafish without (wild-type) or containing (pcare1^{rmc100/rmc100}) the 29 bp deletion in pcare1 were sectioned and stained with antibodies against F-actin (red), Rhodopsin (green) or, in (C) GNAT2 (green). Arrows indicate normal outer segments in control fish and dysmorphic outer segments in mutant fish. Nuclei were stained with DAPI.

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Acknowledgments

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