| Phenotype: | ventral wall of dorsal aorta hematopoietic stem cell runx1 expression increased amount, abnormal |
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| Note: | This phenotype statement describes a gene expression or antibody labeling pattern. Anatomy terms are combined with a gene or antibody and phenotype quality. |
EXPRESSION ANATOMY:
| Name: | ventral wall of dorsal aorta |
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| Synonyms: | AGM, aorta gonad mesonephros region, DA roof, DA-PCV joint, dorsal aorta - posterior cardinal vein joint, DP joint |
| Definition: | Region where blood progenitor markers are expressed. Probable site of definitive hematopoiesis between 36hpf and 4dpf. |
| Ontology: | Anatomy Ontology [ZFA:0005028] |
| Name: | hematopoietic stem cell |
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| Synonyms: | colony forming unit hematopoietic, hematopoietic progenitor cell, hemopoietic progenitor cell, hemopoietic stem cell, HSC |
| Definition: | A stem cell from which all cells of the lymphoid and myeloid lineages develop, including blood cells and cells of the immune system. |
| Ontology: | Anatomy Ontology [ZFA:0009014] |
EXPRESSED GENE:
| Symbol: | runx1 | ||||||||||||
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| Name: | RUNX family transcription factor 1 | ||||||||||||
| Previous Names: | runx1a (1), runxa, aml1 (1) | ||||||||||||
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| Location: | Chr: 1 Mapping Details/Browsers | ||||||||||||
EXPRESSION QUALITY:
| Name: | increased amount |
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| Synonyms: | accessory, increased, increased number, present in greater numbers in organism, supernumerary |
| Definition: | An amount which is relatively high. |
| Ontology: | Phenotypic Quality Ontology [PATO:0000470] |