Search Ontology:
ChEBI

abacavir

Term ID
CHEBI:421707
Synonyms
  • Abacavir
  • ABC
  • {(1S,4R)-4-[2-amino-6-(cyclopropylamino)-9H-purin-9-yl]cyclopent-2-en-1-yl}methanol
  • {(1S-cis)-4-[2-amino-6-(cyclopropylamino)-9H-purin-9-yl]cyclopent-2-en-1-yl}methanol
Definition
A 2,6-diaminopurine that is (1S)-cyclopent-2-en-1-ylmethanol in which the pro-R hydrogen at the 4-position is substituted by a 2-amino-6-(cyclopropylamino)-9H-purin-9-yl group. A nucleoside analogue reverse transcriptase inhibitor (NRTI) with antiretroviral activity against HIV, it is used (particularly as the sulfate) with other antiretrovirals in combination therapy of HIV infection.
References
Ontology
ChEBI  ( EBI )
Relationships
is a type of
has subtype
has_role
inverse has_functional_parent
Phenotype
Phenotype resulting from abacavir
Phenotype where environments contain abacavir
Phenotype modified by environments containing abacavir
Human Disease / Model Data
Citations
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