| Term Name: |
granzyme-mediated apoptotic signaling pathway |
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Search Ontology:
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| Synonyms: |
- apoptotic signaling pathway in response to granzyme
- induction of apoptosis by granzyme
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| Definition: |
The series of molecular signals induced by granzymes which triggers the apoptotic death of a cell. The pathway starts with reception of a granzyme signal, and ends when the execution phase of apoptosis is triggered. Granzymes are serine proteases that are secreted by cytotoxic T cells and natural killer cells to induce apoptosis in target cells.
17158907
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| References: |
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| Ontology: |
GO: Biological Process
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