apoptotic signaling pathway

Term ID

GO:0097190

Synonyms

apoptotic signalling pathway
induction of apoptosis by extracellular signals

Definition

The series of molecular signals which triggers the apoptotic death of a cell. The pathway starts with reception of a signal, and ends when the execution phase of apoptosis is triggered.

References

Reactome:R-HSA-193681
Reactome:R-HSA-204998
Reactome:R-HSA-75157

Ontology

GO: Biological Process QuickGO AmiGO

Relationships

is part of: apoptotic process

apoptotic process Show first 5 Terms
has parts: apoptosome assembly mitochondrial outer membrane permeabilization release of cytochrome c from mitochondria

apoptosome assembly mitochondrial outer membrane permeabilization release of cytochrome c from mitochondria Show first 5 Terms
is a type of: signal transduction

signal transduction Show first 5 Terms
has subtype: extrinsic apoptotic signaling pathway granzyme-mediated apoptotic signaling pathway hormone-mediated apoptotic signaling pathway intrinsic apoptotic signaling pathway

extrinsic apoptotic signaling pathway granzyme-mediated apoptotic signaling pathway hormone-mediated apoptotic signaling pathway intrinsic apoptotic signaling pathway Show first 5 Terms
inverse has_part: apoptotic process

apoptotic process Show first 5 Terms
negatively regulated by: negative regulation of apoptotic signaling pathway

negative regulation of apoptotic signaling pathway Show first 5 Terms
positively regulated by: positive regulation of apoptotic signaling pathway

positive regulation of apoptotic signaling pathway Show first 5 Terms
regulated by: regulation of apoptotic signaling pathway

regulation of apoptotic signaling pathway Show first 5 Terms

Phenotype

Phenotype caused by Genes