granzyme-mediated programmed cell death signaling pathway

Term ID

GO:0140507

Synonyms

• granzyme-mediated cell death signaling pathway

Definition

The series of molecular signals induced by granzymes which triggers the cell death of a cell. The pathway starts with reception of a granzyme signal, and ends when the execution phase of cell death is triggered. Granzymes are serine proteases that are secreted by cytotoxic T cells and natural killer cells to induce cell death in target cells. 32299851

References

Ontology

GO: Biological Process    QuickGO    AmiGO