OBO ID: DOID:684

OBO ID: DOID:684

Citations

(58 total)

Hou, C.Y., Ma, C.Y., Lin, Y.J., Huang, C.L., Wang, H.D., Yuh, C.H. (2022) WNK1-OSR1 Signaling Regulates Angiogenesis-Mediated Metastasis towards Developing a Combinatorial Anti-Cancer Strategy. International Journal of Molecular Sciences. 23(20):

Lu, J.W., Lin, L.I., Sun, Y., Liu, D., Gong, Z. (2022) Effect of Lipopolysaccharides on Liver Tumor Metastasis of twist1a/kras^V12 Double Transgenic Zebrafish. Biomedicines. 10(1):

Monroe, J.D., Fraher, D., Huang, X., Mellett, N.A., Meikle, P.J., Sinclair, A.J., Lirette, S.T., Maihle, N.J., Gong, Z., Gibert, Y. (2022) Identification of novel lipid biomarkers in xmrk- and Myc-induced models of hepatocellular carcinoma in zebrafish. Cancer & metabolism. 10:7

Ning, W., Xu, N., Zhou, C., Zou, L., Quan, J., Yang, H., Lu, Z., Cao, H., Liu, J. (2022) Ethyl Acetate Fraction of Hedyotis diffusa Willd Induces Apoptosis via JNK/Nur77 Pathway in Hepatocellular Carcinoma Cells. Evidence-based complementary and alternative medicine : eCAM. 2022:1932777

Tonon, F., Cemazar, M., Kamensek, U., Zennaro, C., Pozzato, G., Caserta, S., Ascione, F., Grassi, M., Guido, S., Ferrari, C., Cansolino, L., Trotta, F., Kuzmanov, B.G., Forte, G., Martino, F., Perrone, F., Bomben, R., Gattei, V., Elvassore, N., Murano, E., Truong, N.H., Olson, M., Farra, R., Grassi, G., Dapas, B. (2022) 5-Azacytidine Downregulates the Proliferation and Migration of Hepatocellular Carcinoma Cells In Vitro and In Vivo by Targeting miR-139-5p/ROCK2 Pathway. Cancers. 14(7):

Akbari, S., Kunter, İ., Azbazdar, Y., Ozhan, G., Atabey, N., Karagonlar, Z.F., Erdal, E. (2021) LGR5/R-Spo1/Wnt3a axis promotes stemness and aggressive phenotype in hepatoblast-like hepatocellular carcinoma cell lines. Cellular Signalling. 82:109972

Chen, Y., Yang, W., Chen, Q., Liu, Q., Liu, J., Zhang, Y., Li, B., Li, D., Nan, J., Li, X., Wu, H., Xiang, X., Peng, Y., Wang, J., Su, S., Wang, Z. (2021) Prediction of hepatocellular carcinoma risk in patients with chronic liver disease from dynamic modular networks. Journal of translational medicine. 19:122

Huang, C.Y., Chang, Y.J., Wei, P.L., Hung, C.S., Wang, W. (2021) Methyl gallate, gallic acid-derived compound, inhibit cell proliferation through increasing ROS production and apoptosis in hepatocellular carcinoma cells. PLoS One. 16:e0248521

Huang, D., Yang, B., Yao, Y., Liao, M., Zhang, Y., Zeng, Y., Zhang, F., Wang, N., Tong, G. (2021) Autophagic Inhibition of Caveolin-1 by Compound Phyllanthus urinaria L. Activates Ubiquitination and Proteasome Degradation of β-catenin to Suppress Metastasis of Hepatitis B-Associated Hepatocellular Carcinoma. Frontiers in pharmacology. 12:659325

Iscan, E., Ekin, U., Yildiz, G., Oz, O., Keles, U., Suner, A., Cakan-Akdogan, G., Ozhan, G., Nekulova, M., Vojtesek, B., Uzuner, H., Karakülah, G., Alotaibi, H., Ozturk, M. (2021) TAp73β Can Promote Hepatocellular Carcinoma Dedifferentiation. Cancers. 13(4):

Zhang, C., Li, Q., Qin, G., Zhang, Y., Li, C., Han, L., Wang, R., Wang, S., Chen, H., Liu, K., He, C. (2021) Anti-angiogenesis and anti-metastasis effects of Polyphyllin VII on Hepatocellular carcinoma cells in vitro and in vivo. Chinese Medicine. 16:41

Zhu, Y., Yang, D., Duan, X., Zhang, Y., Chen, D., Gong, Z., Liu, C. (2021) Perfluorooctane Sulfonate Promotes Doxycycline-induced Liver Tumor Progression in Male Kras^v12 Transgenic Zebrafish. Environmental research. 196:110962

Fei, F., Sun, S., Li, Q., Pei, Z., Wang, L., Zhang, R., Luo, F., Yu, M., Wang, X. (2020) Combinatorial normalization of liver-derived cytokine pathways alleviates hepatic tumor-associated cachexia in zebrafish. Cancer research. 81(4):873-884

Kim, E.A., Lee, J.H., Heo, S.J., Jeon, Y.J. (2020) Saringosterol acetate isolated from Hizikia fusiforme, an edible brown alga, suppressed hepatocellular carcinoma growth and metastasis in a zebrafish xenograft model. Chemico-biological interactions. 335:109362

Mawed, S.A., He, Y., Zhang, J., Mei, J. (2020) Strategy of Hepatic Metabolic Defects Induced by beclin1 Heterozygosity in Adult Zebrafish. International Journal of Molecular Sciences. 21(4):

Poté, N., Cros, J., Laouirem, S., Raffenne, J., Negrão, M., Albuquerque, M., Bedossa, P., Godinho Ferreira, M., Ait Si Ali, S., Fior, R., Paradis, V. (2020) The histone acetyltransferase hMOF promotes vascular invasion in hepatocellular carcinoma. Liver international : official journal of the International Association for the Study of the Liver. 40(4):956-967

Topel, H., Bagirsakci, E., Comez, D., Bagci, G., Cakan-Akdogan, G., Atabey, N. (2020) lncRNA HOTAIR overexpression induced downregulation of c-Met signaling promotes hybrid epithelial/mesenchymal phenotype in hepatocellular carcinoma cells. Cell communication and signaling : CCS. 18:110

Wu, S.Y., Yang, W.Y., Cheng, C.C., Hsiao, M.C., Tsai, S.L., Lin, H.K., Lin, K.H., Yuh, C.H. (2020) Low Molecular Weight Fucoidan Prevents Radiation-Induced Fibrosis and Secondary Tumors in a Zebrafish Model. Cancers. 12(6):

Xu, J., Yan, B., Zhang, L., Zhou, L., Zhang, J., Yu, W., Dong, X., Yao, L., Shan, L. (2020) Theabrownin Induces Apoptosis and Tumor Inhibition of Hepatocellular Carcinoma Huh7 Cells Through ASK1-JNK-c-Jun Pathway. OncoTargets and therapy. 13:8977-8987

Chaturantabut, S., Shwartz, A., Evason, K.J., Cox, A.G., Labella, K., Schepers, A.G., Yang, S., Aravena, M., Houvras, Y., Mancio-Silva, L., Romano, S., Gorelick, D.A., Cohen, D.E., Zon, L.I., Bhatia, S.N., North, T.E., Goessling, W. (2019) Estrogen Activation of G protein-coupled Estrogen Receptor 1 Regulates Phosphoinositide 3-kinase and mTOR Signaling to Promote Liver Growth in Zebrafish and Proliferation of Human Hepatocytes. Gastroenterology. 156(6):1788-1804.e13

Huo, X., Li, H., Li, Z., Yan, C., Agrawal, I., Mathavan, S., Liu, J., Gong, Z. (2019) Transcriptomic profiles of tumor-associated neutrophils reveal prominent roles in enhancing angiogenesis in liver tumorigenesis in zebrafish. Scientific Reports. 9:1509

Kalasekar, S.M., Kotiyal, S., Conley, C., Phan, C., Young, A., Evason, K.J. (2019) Heterogeneous beta-catenin activation is sufficient to cause hepatocellular carcinoma in zebrafish. Biology Open. 8(10):

Li, H., Li, Y., Lu, J.W., Huo, X., Gong, Z. (2019) Liver-specific androgen receptor knockout attenuates early liver tumor development in zebrafish. Scientific Reports. 9:10645

Li, J., Zhang, Y., Cai, C., Rong, X., Shao, M., Li, J., Yang, C., Yu, G. (2019) Collaborative assembly of doxorubicin and galactosyl diblock glycopolymers for targeted drug delivery of hepatocellular carcinoma. Biomaterials science. 8(1):189-200

Li, Y., Agrawal, I., Gong, Z. (2019) Reversion of tumor hepatocytes to normal hepatocytes during liver tumor regression in an oncogene transgenic zebrafish model. Disease models & mechanisms. 12(10):

Lin, H.S., Huang, Y.L., Wang, Y.S., Hsiao, E., Hsu, T.A., Shiao, H.Y., Jiaang, W.T., Sampurna, B.P., Lin, K.H., Wu, M.S., Lai, G.M., Yuh, C.H. (2019) Identification of Novel Anti-Liver Cancer Small Molecules with Better Therapeutic Index than Sorafenib via Zebrafish Drug Screening Platform. Cancers. 11(6)

Su, Z.L., Su, C.W., Huang, Y.L., Yang, W.Y., Sampurna, B.P., Ouchi, T., Lee, K.L., Wu, C.S., Wang, H.D., Yuh, C.H. (2019) A Novel AURKA Mutant-Induced Early-Onset Severe Hepatocarcinogenesis Greater than Wild-Type via Activating Different Pathways in Zebrafish. Cancers. 11(7)

Wei, P.L., Huang, C.Y., Chang, Y.J. (2019) Propyl gallate inhibits hepatocellular carcinoma cell growth through the induction of ROS and the activation of autophagy. PLoS One. 14:e0210513

Yang, Q., Yan, C., Wang, X., Gong, Z. (2019) Leptin induces muscle wasting in kras-driven hepatocellular carcinoma (HCC) model in zebrafish. Disease models & mechanisms. 12(2):

Yang, W.Y., Rao, P.S., Luo, Y.C., Lin, H.K., Huang, S.H., Yang, J.M., Yuh, A.C. (2019) Omics-based Investigation of Diet-induced Obesity Synergized with HBx, Src, and p53 Mutation Accelerating Hepatocarcinogenesis in Zebrafish Model. Cancers. 11(12):

Baell, J.B., Leaver, D.J., Hermans, S.J., Kelly, G.L., Brennan, M.S., Downer, N.L., Nguyen, N., Wichmann, J., McRae, H.M., Yang, Y., Cleary, B., Lagiakos, H.R., Mieruszynski, S., Pacini, G., Vanyai, H.K., Bergamasco, M.I., May, R.E., Davey, B.K., Morgan, K.J., Sealey, A.J., Wang, B., Zamudio, N., Wilcox, S., Garnham, A.L., Sheikh, B.N., Aubrey, B.J., Doggett, K., Chung, M.C., de Silva, M., Bentley, J., Pilling, P., Hattarki, M., Dolezal, O., Dennis, M.L., Falk, H., Ren, B., Charman, S.A., White, K.L., Rautela, J., Newbold, A., Hawkins, E.D., Johnstone, R.W., Huntington, N.D., Peat, T.S., Heath, J.K., Strasser, A., Parker, M.W., Smyth, G.K., Street, I.P., Monahan, B.J., Voss, A.K., Thomas, T. (2018) Inhibitors of histone acetyltransferases KAT6A/B induce senescence and arrest tumour growth. Nature. 560(7717):253-257

de Oliveira, S., Houseright, R.A., Graves, A.L., Golenberg, N., Korte, B.G., Miskolci, V., Huttenlocher, A. (2018) Metformin modulates innate immune-mediated inflammation and early progression of NAFLD-associated hepatocellular carcinoma in zebrafish. Journal of hepatology. 70(4):710-721

Gunes, A., Bagirsakci, E., Iscan, E., Cakan-Akdogan, G., Aykutlu, U., Senturk, S., Ozhan, G., Erdal, E., Nart, D., Barbet, F.Y., Atabey, N. (2018) Thioredoxin interacting protein promotes invasion in hepatocellular carcinoma. Oncotarget. 9:36849-36866

Karkampouna, S., van der Helm, D., Gray, P.C., Chen, L., Klima, I., Grosjean, J., Burgmans, M.C., Farina-Sarasqueta, A., Snaar-Jagalska, E.B., Stroka, D.M., Terracciano, L., van Hoek, B., Schaapherder, A.F., Osanto, S., Thalmann, G.N., Verspaget, H.W., Coenraad, M.J., Kruithof-de Julio, M. (2018) CRIPTO promotes an aggressive tumour phenotype and resistance to treatment in hepatocellular carcinoma. The Journal of pathology. 245(3):297-310

Yao, Y., Sun, S., Wang, J., Fei, F., Dong, Z., Ke, A.W., He, R., Wang, L., Zhang, L., Ji, M.B., Li, Q., Yu, M., Shi, G.M., Fan, J., Gong, Z., Wang, X. (2018) Canonical Wnt signaling remodels lipid metabolism in zebrafish hepatocytes following Ras oncogenic insult. Cancer research. 78(19):5548-5560

Bartucci, M., Hussein, M.S., Huselid, E., Flaherty, K., Patrizii, M., Laddha, S.V., Kui, C., Bigos, R.A., Gilleran, J.A., El Ansary, M.M.S., Awad, M.A.M., Kimball, S.D., Augeri, D.J., Sabaawy, H.E. (2017) Synthesis and Characterization of Novel BMI1 Inhibitors Targeting Cellular Self-Renewal in Hepatocellular Carcinoma. Targeted oncology. 12(4):449-462

Huang, S.J., Cheng, C.L., Chen, J.R., Gong, H.Y., Liu, W., Wu, J.L. (2017) Inducible liver-specific overexpression of gankyrin in zebrafish results in spontaneous intrahepatic cholangiocarcinoma and hepatocellular carcinoma formation. Biochemical and Biophysical Research Communications. 490(3):1052-1058

Li, Y., Li, H., Spitsbergen, J.M., Gong, Z. (2017) Males develop faster and more severe hepatocellular carcinoma than females in kras^V12 transgenic zebrafish.. Scientific Reports. 7:41280

Tu, H.C., Hsiao, Y.C., Yang, W.Y., Tsai, S.L., Lin, H.K., Liao, C.Y., Lu, J.W., Chou, Y.T., Wang, H.D., Yuh, C.H. (2017) Up-regulation of golgi α-mannosidase IA and down-regulation of golgi α-mannosidase IC activates unfolded protein response during hepatocarcinogenesis. Hepatology communications. 1:230-247

Yan, C., Yang, Q., Gong, Z. (2017) Tumor-associated neutrophils and macrophages promote gender disparity in hepatocellular carcinoma in zebrafish. Cancer research. 77(6):1395-1407

Yang, J., Pei, H., Luo, H., Fu, A., Yang, H., Hu, J., Zhao, C., Chai, L., Chen, X., Shao, X., Wang, C., Wu, W., Wan, L., Ye, H., Qiu, Q., Peng, A., Wei, Y., Yang, L., Chen, L. (2017) Non-toxic dose of liposomal honokiol suppresses metastasis of hepatocellular carcinoma through destabilizing EGFR and inhibiting the downstream pathways. Oncotarget. 8(1):915-932

Yang, Q., Yan, C., Yin, C., Gong, Z. (2017) Serotonin Activated Hepatic Stellate Cells Contribute to Sex Disparity in Hepatocellular Carcinoma. Cellular and molecular gastroenterology and hepatology. 3:484-499

Kumar, S., Lockwood, N., Ramel, M.C., Correia, T., Ellis, M., Alexandrov, Y., Andrews, N., Patel, R., Bugeon, L., Dallman, M.J., Brandner, S., Arridge, S., Katan, M., McGinty, J., Frankel, P., French, P.M. (2016) Quantitative in vivo optical tomography of cancer progression & vasculature development in adult zebrafish. Oncotarget. 7(28):43939-43948

Tonon, F., Zennaro, C., Dapas, B., Carraro, M., Mariotti, M., Grassi, G. (2016) Rapid and cost-effective xenograft hepatocellular carcinoma model in Zebrafish for drug testing. International journal of pharmaceutics. 515(1-2):583-591

Tseng, C.H., Chen, Y.R., Tzeng, C.C., Liu, W., Chou, C.K., Chiu, C.C., Chen, Y.L. (2016) Discovery of indeno[1,2-b]quinoxaline derivatives as potential anticancer agents. European Journal of Medicinal Chemistry. 108:258-273

Zhao, Y., Huang, X., Ding, T.W., Gong, Z. (2016) Enhanced angiogenesis, hypoxia and neutrophil recruitment during Myc-induced liver tumorigenesis in zebrafish. Scientific Reports. 6:31952

Evason, K.J., Francisco, M.T., Juric, V., Balakrishnan, S., Lopez Pazmino, M.D., Gordan, J.D., Kakar, S., Spitsbergen, J., Goga, A., Stainier, D.Y. (2015) Identification of Chemical Inhibitors of β-Catenin-Driven Liver Tumorigenesis in Zebrafish. PLoS Genetics. 11:e1005305

Fujisawa, K., Terai, S., Matsumoto, T., Takami, T., Yamamoto, N., Nishina, H., Furutani-Seiki, M., Sakaida, I. (2015) Evidence for a Role of the Transcriptional Regulator Maid in Tumorigenesis and Aging. PLoS One. 10:e0129950

Li, Z., Zheng, W., Li, H., Li, C., Gong, Z. (2015) Synergistic Induction of Potential Warburg Effect in Zebrafish Hepatocellular Carcinoma by Co-Transgenic Expression of Myc and xmrk Oncogenes. PLoS One. 10:e0132319

Lu, J.W., Ho, Y.J., Yang, Y.J., Liao, H.A., Ciou, S.C., Lin, L.I., Ou, D.L. (2015) Zebrafish as a disease model for studying human hepatocellular carcinoma. World journal of gastroenterology. 21:12042-12058

Yan, C., Huo, X., Wang, S., Feng, Y., Gong, Z. (2015) Stimulation of hepatocarcinogenesis by neutrophils upon induction of oncogenic kras expression in transgenic zebrafish. Journal of hepatology. 63(2):420-8

Chew, T.W., Liu, X.J., Liu, L., Spitsbergen, J.M., Gong, Z., and Low, B.C. (2014) Crosstalk of Ras and Rho: activation of RhoA abates Kras-induced liver tumorigenesis in transgenic zebrafish models. Oncogene. 33(21):2717-27

Lessel, D., Vaz, B., Halder, S., Lockhart, P.J., Marinovic-Terzic, I., Lopez-Mosqueda, J., Philipp, M., Sim, J.C., Smith, K.R., Oehler, J., Cabrera, E., Freire, R., Pope, K., Nahid, A., Norris, F., Leventer, R.J., Delatycki, M.B., Barbi, G., von Ameln, S., Högel, J., Degoricija, M., Fertig, R., Burkhalter, M.D., Hofmann, K., Thiele, H., Altmüller, J., Nürnberg, G., Nürnberg, P., Bahlo, M., Martin, G.M., Aalfs, C.M., Oshima, J., Terzic, J., Amor, D.J., Dikic, I., Ramadan, K., Kubisch, C. (2014) Mutations in SPRTN cause early onset hepatocellular carcinoma, genomic instability and progeroid features. Nature Genetics. 46:1239-44

Lu, J.W., Liao, C.Y., Yang, W.Y., Lin, Y.M., Jin, S.L., Wang, H.D., and Yuh, C.H. (2014) Overexpression of endothelin 1 triggers hepatocarcinogenesis in zebrafish and promotes cell proliferation and migration through the AKT pathway. PLoS One. 9(1):e85318

Mudbhary, R., Hoshida, Y., Chernyavskaya, Y., Jacob, V., Villanueva, A., Fiel, M.I., Chen, X., Kojima, K., Thung, S., Bronson, R.T., Lachenmayer, A., Revill, K., Alsinet, C., Sachidanandam, R., Desai, A., SenBanerjee, S., Ukomadu, C., Llovet, J.M., and Sadler, K.C. (2014) UHRF1 overexpression drives DNA hypomethylation and hepatocellular carcinoma. Cancer Cell. 25(2):196-209

Zheng, W., Li, Z., Nguyen, A.T., Li, C., Emelyanov, A., Gong, Z. (2014) Xmrk, kras and myc transgenic zebrafish liver cancer models share molecular signatures with subsets of human hepatocellular carcinoma. PLoS One. 9:e91179

Zhong, L., Fu, X.Y., Zou, C., Yang, L.L., Zhou, S., Yang, J., Tang, Y., Cheng, C., Li, L.L., Xiang, R., Chen, L.J., Chen, Y.Z., Wei, Y.Q., Yang, S.Y. (2014) A preclinical evaluation of a novel multikinase inhibitor, SKLB-329, as a therapeutic agent against hepatocellular carcinoma. International Journal of Cancer. 135(12):2972-83

Lu, J.W., Yang, W.Y., Tsai, S.M., Lin, Y.M., Chang, P.H., Chen, J.R., Wang, H.D., Wu, J.L., Jin, S.L., and Yuh, C.H. (2013) Liver-Specific Expressions of HBx and src in the p53 Mutant Trigger Hepatocarcinogenesis in Zebrafish. PLoS One. 8(10):e76951