Gene

rxrab

ID
ZDB-GENE-990415-243
Name
retinoid x receptor, alpha b
Symbol
rxrab Nomenclature History
Previous Names
  • rxra
  • rxrg
  • etID309731.5 (1)
  • NR2B1-A (1)
  • RXRalpha-A (1)
Type
protein_coding_gene
Location
Chr: 5 Mapping Details/Browsers
Description
Enables nuclear receptor activity. Predicted to be involved in several processes, including regulation of transcription by RNA polymerase II; response to retinoic acid; and retinoic acid receptor signaling pathway. Predicted to act upstream of or within regulation of DNA-templated transcription. Predicted to be located in nucleus. Predicted to be part of RNA polymerase II transcription regulator complex. Is expressed in several structures, including cardiovascular system; retina; segmental plate; swim bladder bud; and tail bud. Human ortholog(s) of this gene implicated in pancreatic cancer. Orthologous to human RXRA (retinoid X receptor alpha).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
20 figures from 9 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Allele Type Localization Consequence Mutagen Supplier
sa1205Allele with one point mutationUnknownPremature StopENU
sa11783Allele with one point mutationUnknownSplice SiteENU
sa16874Allele with one point mutationUnknownPremature StopENU
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Sequence Targeting Reagents
No data available
Human Disease
Associated With rxrab Human Ortholog
No data available
Associated With rxrab Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR000536 Nuclear hormone receptor, ligand-binding domain
Domain IPR001628 Zinc finger, nuclear hormone receptor-type
Domain IPR021780 Nuclear/hormone receptor activator site AF-1
Family IPR000003 Retinoid X receptor/HNF4
Family IPR001723 Nuclear hormone receptor
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Domain Details Per Protein
Protein Length Nuclear hormone receptor Nuclear/hormone receptor activator site AF-1 Nuclear hormone receptor family NR2 subfamily Nuclear hormone receptor, ligand-binding domain Nuclear hormone receptor-like domain superfamily Retinoid X receptor/HNF4 Zinc finger, NHR/GATA-type Zinc finger, nuclear hormone receptor-type
UniProtKB:A0A8M3ASV4 494
UniProtKB:Q90415 379
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Transcripts
Genome Browsers
Genome Build: GRCz11Chromosome: 5
Type Name Annotation Method Has Havana Data Length (nt) Analysis
mRNA rxrab-201 (1) Ensembl 1,721 nt
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Interactions and Pathways
Antibodies
No data available
Plasmids
No data available
Constructs
No data available
Marker Relationships
Relationship Marker Type Marker Accession Numbers Citations
Contained inBACCH73-262B19ZFIN Curated Data
EncodesESTu29894 (2)
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Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Species Symbol Chromosome Accession # Evidence
HumanRXRA9
Conserved genome location (synteny) (2)
Phylogenetic tree (1)
Amino acid sequence comparison (5)
MouseRxra2
Phylogenetic tree (1)
Amino acid sequence comparison (3)
Citations
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