ZFIN is now using GRCz12tu for Genomic Data
Gene
hdac3
- ID
- ZDB-GENE-040426-847
- Name
- histone deacetylase 3
- Symbol
- hdac3 Nomenclature History
- Previous Names
-
- zgc:55927 (1)
- Type
- protein_coding_gene
- Location
- Chr: 14 Mapping Details/Browsers
- Genome Assembly
- GRCz12tu
- Annotation Status
- Current
- Description
- Predicted to enable several functions, including histone modifying activity; protein de-2-hydroxyisobutyrylase activity; and protein lysine delactylase activity. Acts upstream of or within several processes, including angiogenesis; liver development; and posterior lateral line development. Predicted to be located in cytoplasm and nucleus. Predicted to be part of histone deacetylase complex and transcription repressor complex. Is expressed in several structures, including axial blood vessel; blood vessel; digestive system; otic vesicle; and sensory system. Human ortholog(s) of this gene implicated in lung non-small cell carcinoma. Orthologous to human HDAC3 (histone deacetylase 3).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 15 figures from 8 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- MGC:55927 (1 image)
- MGC:55927 (7 images)
Wild Type Expression Summary
- All Phenotype Data
- 15 figures from 5 publications
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Additional Resources | Length | Histone deacetylase domain | Histone deacetylase domain superfamily | Ureohydrolase domain superfamily |
|---|---|---|---|---|---|
| UniProtKB:Q803C3 | InterPro | 428 |
- Genome Browsers
Interactions and Pathways
No data available
Plasmids
No data available
- Genome Browsers