Gene
upf1
- ID
- ZDB-GENE-040426-2836
- Name
- UPF1 RNA helicase and ATPase
- Symbol
- upf1 Nomenclature History
- Previous Names
-
- rent1
- wu:fi40f07
- wu:fj48a01
- zgc:55472 (1)
- Type
- protein_coding_gene
- Location
- Chr: 2 Mapping Details/Browsers
- Description
- Predicted to have RNA binding activity and RNA helicase activity. Involved in chordate embryonic development and nuclear-transcribed mRNA catabolic process, nonsense-mediated decay. Predicted to localize to cytoplasm. Orthologous to human UPF1 (UPF1 RNA helicase and ATPase).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 5 figures from 4 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- MGC:55472 (1 image)
Wild Type Expression Summary
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Domain | IPR006935 | Helicase/UvrB, N-terminal |
| Domain | IPR018999 | RNA helicase UPF1, Cys/His rich zinc-binding domain |
| Domain | IPR040812 | RNA helicase UPF1, 1B domain |
| Domain | IPR041677 | DNA2/NAM7 helicase, helicase domain |
| Domain | IPR041679 | DNA2/NAM7 helicase-like, C-terminal |
| Domain | IPR047187 | Upf1-like, C-terminal helicase domain |
| Family | IPR045055 | DNA2/NAM7-like helicase |
| Homologous_superfamily | IPR027417 | P-loop containing nucleoside triphosphate hydrolase |
Domain Details Per Protein
| Protein | Length | DNA2/NAM7 helicase, helicase domain | DNA2/NAM7 helicase-like, C-terminal | DNA2/NAM7-like helicase | Helicase/UvrB, N-terminal | P-loop containing nucleoside triphosphate hydrolase | RNA helicase UPF1, 1B domain | RNA helicase UPF1, Cys/His rich zinc-binding domain | Upf1-like, C-terminal helicase domain |
|---|---|---|---|---|---|---|---|---|---|
|
UniProtKB:Q7ZVZ4
|
1100 | ||||||||
|
UniProtKB:F1RCY6
|
1100 | ||||||||
|
UniProtKB:A0A8I7ZFH8
|
|||||||||
|
UniProtKB:A0A8M2BAV2
|
1099 |
Interactions and Pathways
No data available
Plasmids