Gene
hs6st2
- ID
- ZDB-GENE-030909-14
- Name
- heparan sulfate 6-O-sulfotransferase 2
- Symbol
- hs6st2 Nomenclature History
- Previous Names
- Type
- protein_coding_gene
- Location
- Chr: 14 Mapping Details/Browsers
- Description
- Enables heparan sulfate 6-O-sulfotransferase activity. Acts upstream of or within branching involved in blood vessel morphogenesis and embryonic eye morphogenesis. Predicted to be located in membrane. Is expressed in several structures, including immature eye; nervous system; neural keel; somite; and tail bud. Human ortholog(s) of this gene implicated in Paganini-Miozzo syndrome. Orthologous to human HS6ST2 (heparan sulfate 6-O-sulfotransferase 2).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 9 figures from 4 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
Wild Type Expression Summary
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| Paganini-Miozzo syndrome | Alliance | ?Paganini-Miozzo syndrome | 301025 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | Heparan sulphate 6-sulfotransferase/Protein-tyrosine sulfotransferase | P-loop containing nucleoside triphosphate hydrolase | Sulfotransferase |
|---|---|---|---|---|
|
UniProtKB:Q800H9
|
468 |
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
hs6st2-201
(1)
|
Ensembl | 2,476 nt |
Interactions and Pathways
No data available
Plasmids
No data available