Gene

foxh1

ID

ZDB-GENE-000616-15

Name

forkhead box H1

Symbol

foxh1 Nomenclature History

Previous Names

etID62177.12 (1)
fast1
fast (1)
fe26b06
schmalspur
sur
uncle freddy (1)
unf (1)
wu:fe26b06 (1)
wu:fi30c08 (1)
wu:fi32b01 (1)

Type

protein_coding_gene

Location

Chr: 12 Mapping Details/Browsers

Description

Exhibits DNA-binding transcription repressor activity, RNA polymerase II-specific; RNA polymerase II regulatory region sequence-specific DNA binding activity; and SMAD binding activity. Involved in several processes, including embryonic morphogenesis; nervous system development; and regionalization. Localizes to chromatin. Is expressed in several structures, including nervous system; oocyte; pericardial region; presumptive diencephalon; and ventral mesoderm. Orthologous to human FOXH1 (forkhead box H1).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

10 figures from 7 publications

Cross-Species Comparison

High Throughput Data

GEO (1)

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

MGC:55221 (5 images)

Wild Type Expression Summary

Phenotype

All Phenotype Data: 32 figures from 13 publications
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With foxh1 Human Ortholog

No data available

Associated With foxh1 Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Conserved_site	IPR030456	Fork head domain conserved site 2
Domain	IPR001766	Fork head domain
Domain	IPR047511	Forkhead box protein H1, forkhead domain
Family	IPR052327	Activin-responsive transcriptional regulator
Homologous_superfamily	IPR036388	Winged helix-like DNA-binding domain superfamily
Homologous_superfamily	IPR036390	Winged helix DNA-binding domain superfamily