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General Information
ZIRC
ZFIN ID: ZDB-GENE-980526-212
Gene Name: distal-less homeobox 2a
Gene Symbol: dlx2a
GO Details
Ontology Qualifier Term Evidence Inferred From Annotation Extension Reference(s)
Molecular Function DNA binding IEA InterPro:IPR000047 ZFIN Electronic Annotation
DNA binding IEA InterPro:IPR001356 ZFIN Electronic Annotation
DNA binding IEA InterPro:IPR009057 ZFIN Electronic Annotation
DNA binding IEA InterPro:IPR020479 ZFIN Electronic Annotation
DNA binding IEA UniProtKB-KW:KW-0238 ZFIN Electronic Annotation
DNA binding IEA UniProtKB-KW:KW-0371 ZFIN Electronic Annotation
DNA-binding transcription factor activity IBA MGI:MGI:94902, PANTHER:PTN002802863, MGI:MGI:1919200, UniProtKB:Q9H9S0, MGI:MGI:2669849 Gaudet et al., 2010
RNA polymerase II cis-regulatory region sequence-specific DNA binding IBA PANTHER:PTN002802863, UniProtKB:Q92988, MGI:MGI:101926, MGI:MGI:2669849 Gaudet et al., 2010
sequence-specific DNA binding IBA MGI:MGI:94901, MGI:MGI:94902, PANTHER:PTN002802863, UniProtKB:Q92988, UniProtKB:O95231, MGI:MGI:1919200, MGI:MGI:101926, MGI:MGI:2669849, UniProtKB:Q9H9S0 Gaudet et al., 2010
sequence-specific DNA binding IEA InterPro:IPR017970 ZFIN Electronic Annotation
Cellular Component nucleus IBA RGD:1303178, MGI:MGI:94901, MGI:MGI:94902, FB:FBgn0000529, MGI:MGI:94903, FB:FBgn0000157, MGI:MGI:101926, UniProtKB:Q9H9S0, UniProtKB:Q6NSW7, WB:WBGene00000446, PANTHER:PTN002802863, UniProtKB:A7Y7W3, WB:WBGene00013583, UniProtKB:P56177, MGI:MGI:1919200, MGI:MGI:2669849 Gaudet et al., 2010
nucleus IEA UniProtKB-KW:KW-0539 ZFIN Electronic Annotation
nucleus IEA UniProtKB-SubCell:SL-0191 UniProt-GOA
Biological Process cartilage development IGI MO1-dlx1a, MO2-dlx2a Sperber et al., 2008
cartilage development IMP MO2-dlx2a Sperber et al., 2008
cell differentiation IBA PANTHER:PTN000675745, MGI:MGI:94901, MGI:MGI:94902, MGI:MGI:101927, MGI:MGI:101926 Gaudet et al., 2010
embryonic viscerocranium morphogenesis IGI MO1-dlx1a, MO2-dlx2a Talbot et al., 2010
embryonic viscerocranium morphogenesis IMP MO2-polr1c Kwong et al., 2017
multicellular organism development IEA UniProtKB-KW:KW-0217 ZFIN Electronic Annotation
negative regulation of photoreceptor cell differentiation ISS UniProtKB:P40764 GOA et al., 2007
negative regulation of transcription by RNA polymerase II IBA PANTHER:PTN002802895, MGI:MGI:94902 Gaudet et al., 2010
neural crest cell development IMP MO2-dlx2a Sperber et al., 2008
peripheral nervous system development IMP MO2-dlx2a Sperber et al., 2008
pharyngeal system development IMP MO2-dlx2a Sperber et al., 2008
positive regulation of amacrine cell differentiation ISS UniProtKB:P40764 GOA et al., 2007
positive regulation of transcription by RNA polymerase II IBA PANTHER:PTN000675745, MGI:MGI:94901, MGI:MGI:94902, MGI:MGI:94903, UniProtKB:P56177, MGI:MGI:101926 Gaudet et al., 2010
regulation of transcription by RNA polymerase II IBA WB:WBGene00000446, RGD:1303178, MGI:MGI:94901, MGI:MGI:94902, PANTHER:PTN002802863, UniProtKB:Q92988, UniProtKB:P56177, UniProtKB:O95231, MGI:MGI:1919200, MGI:MGI:101926, MGI:MGI:2669849, UniProtKB:Q9H9S0 Gaudet et al., 2010
regulation of transcription, DNA-templated IEA InterPro:IPR017970 ZFIN Electronic Annotation
ribosome biogenesis IMP polr1ahi3639Tg/hi3639Tg Weaver et al., 2015