ZFIN

ZFIN ID: ZDB-TGCONSTRCT-070410-2

ZFIN ID: ZDB-TGCONSTRCT-070410-2

CITATIONS (45 total)

Transgenic Construct Name:	Tg(gfap:EGFP)
Transgenic Construct Symbol:	Tg(gfap:EGFP)

Lee, E.J., Kim, M., Park, S., Shim, J.H., Cho, H.J., Park, J.A., Park, K., Lee, D., Kim, J.H., Jeong, H., Matsuzaki, F., Kim, S.Y., Kim, J., Yang, H., Lee, J.S., Kim, J.W. (2025) Restoration of retinal regenerative potential of Müller glia by disrupting intercellular Prox1 transfer. Nature communications. 16:2928

Lu, C., Hyde, D.R. (2024) Cytokines IL-1β and IL-10 are required for Müller glia proliferation following light damage in the adult zebrafish retina. Frontiers in cell and developmental biology. 12:1406330

Boyd, P., Campbell, L.J., Hyde, D.R. (2023) Clcf1/Crlf1a-mediated signaling is neuroprotective and required for Müller glia proliferation in the light-damaged zebrafish retina. Frontiers in cell and developmental biology. 11:1142586

Castro, V.L., Paz, D., Virrueta, V., Estevao, I.L., Grajeda, B.I., Ellis, C.C., Quintana, A.M. (2023) Missense and nonsense mutations of the zebrafish hcfc1a gene result in contrasting mTor and radial glial phenotypes. Gene. 864:147290

Lyu, P., Iribarne, M., Serjanov, D., Zhai, Y., Hoang, T., Campbell, L.J., Boyd, P., Palazzo, I., Nagashima, M., Silva, N.J., Hitchcock, P.F., Qian, J., Hyde, D.R., Blackshaw, S. (2023) Common and divergent gene regulatory networks control injury-induced and developmental neurogenesis in zebrafish retina. Nature communications. 14:8477

Palsamy, K., Chen, J.Y., Skaggs, K., Qadeer, Y., Connors, M., Cutler, N., Richmond, J., Kommidi, V., Poles, A., Affrunti, D., Powell, C., Goldman, D., Parent, J.M. (2023) Microglial depletion after brain injury prolongs inflammation and impairs brain repair, adult neurogenesis and pro-regenerative signaling. Glia. 71(11):2642-2663

Iribarne, M., Hyde, D.R. (2022) Different inflammation responses modulate Müller glia proliferation in the acute or chronically damaged zebrafish retina. Frontiers in cell and developmental biology. 10:892271

Mitra, S., Devi, S., Lee, M.S., Jui, J., Sahu, A., Goldman, D. (2022) Vegf signaling between Müller glia and vascular endothelial cells is regulated by immune cells and stimulates retina regeneration. Proceedings of the National Academy of Sciences of the United States of America. 119:e2211690119

Halabi, R., Watterston, C., Hehr, C.L., Mori-Kreiner, R., Childs, S.J., McFarlane, S. (2021) Semaphorin 3fa Controls Ocular Vascularization From the Embryo Through to the Adult. Investigative ophthalmology & visual science. 62:21

Hentig, J., Cloghessy, K., Lahne, M., Jung, Y.J., Petersen, R.A., Morris, A.C., Hyde, D.R. (2021) Zebrafish Blunt-Force TBI Induces Heterogenous Injury Pathologies That Mimic Human TBI and Responds with Sonic Hedgehog-Dependent Cell Proliferation across the Neuroaxis. Biomedicines. 9(8):

Koun, S., Eom, Y., Kim, M.J., Kim, S., Lee, I.H., Park, H.C., Song, J.S., Kim, H.M. (2021) Development of an experimental model for ocular toxicity screening in Zebrafish. Biochemical and Biophysical Research Communications. 559:155-160

Campbell, L.J., Hobgood, J.S., Jia, M., Boyd, P., Hipp, R.I., Hyde, D.R. (2020) Notch3 and DeltaB maintain Müller glia quiescence and act as negative regulators of regeneration in the light-damaged zebrafish retina. Glia. 69(3):546-566

Hoang, T., Wang, J., Boyd, P., Wang, F., Santiago, C., Jiang, L., Yoo, S., Lahne, M., Todd, L.J., Jia, M., Saez, C., Keuthan, C., Palazzo, I., Squires, N., Campbell, W.A., Rajaii, F., Parayil, T., Trinh, V., Kim, D.W., Wang, G., Campbell, L.J., Ash, J., Fischer, A.J., Hyde, D.R., Qian, J., Blackshaw, S. (2020) Gene regulatory networks controlling vertebrate retinal regeneration. Science (New York, N.Y.). 370(6519):

Lee, M., Wan, J., Goldman, D. (2020) Tgfb3 collaborates with PP2A and Notch signaling pathways to inhibit retina regeneration. eLIFE. 9:

Iribarne, M., Hyde, D.R., Masai, I. (2019) TNFα Induces Müller Glia to Transition From Non-proliferative Gliosis to a Regenerative Response in Mutant Zebrafish Presenting Chronic Photoreceptor Degeneration. Frontiers in cell and developmental biology. 7:296

Nelson, C.M., Lennon, V.A., Lee, H., Krug, R.G., Kamalova, A., Madigan, N.N., Clark, K.J., Windebank, A.J., Henley, J.R. (2019) Glucocorticoids Target Ependymal Glia and Inhibit Repair of the Injured Spinal Cord. Frontiers in cell and developmental biology. 7:56

Elsaeidi, F., Macpherson, P., Mills, E.A., Jui, J., Flannery, J.G., Goldman, D. (2018) Notch suppression collaborates with Ascl1 and Lin28 to unleash a regenerative response in fish retina, but not in mice. The Journal of neuroscience : the official journal of the Society for Neuroscience. 38(9):2246-2261

Lahne, M., Piekos, S.M., O'Neill, J., Ackerman, K.M., Hyde, D.R. (2018) Photo-regulation of rod precursor cell proliferation. Experimental Eye Research. 178:148-159

Ranski, A.H., Kramer, A.C., Morgan, G.W., Perez, J.L., Thummel, R. (2018) Characterization of retinal regeneration in adult zebrafish following multiple rounds of phototoxic lesion. PeerJ. 6:e5646

Gorsuch, R.A., Lahne, M., Yarka, C.E., Petravick, M.E., Li, J., Hyde, D.R. (2017) Sox2 regulates Müller glia reprogramming and proliferation in the regenerating zebrafish retina via Lin28 and Ascl1a. Experimental Eye Research. 161:174-192

Thomas, J.L., Morgan, G.W., Dolinski, K.M., Thummel, R. (2017) Characterization of the pleiotropic roles of Sonic Hedgehog during retinal regeneration in adult zebrafish. Experimental Eye Research. 166:106-115

Wan, J., Goldman, D. (2017) Opposing Actions of Fgf8a on Notch Signaling Distinguish Two Muller Glial Cell Populations that Contribute to Retina Growth and Regeneration. Cell Reports. 19:849-862

Thomas, J.L., Ranski, A.H., Morgan, G.W., Thummel, R. (2016) Reactive Gliosis in the Adult Zebrafish Retina. Experimental Eye Research. 143:98-109

Lahne, M., Li, J., Marton, R.M., Hyde, D.R. (2015) Actin-Cytoskeleton- and Rock-Mediated INM Are Required for Photoreceptor Regeneration in the Adult Zebrafish Retina. The Journal of neuroscience : the official journal of the Society for Neuroscience. 35:15612-34

Conner, C., Ackerman, K.M., Lahne, M., Hobgood, J.S., Hyde, D.R. (2014) Repressing Notch Signaling and Expressing TNFα Are Sufficient to Mimic Retinal Regeneration by Inducing Müller Glial Proliferation to Generate Committed Progenitor Cells. The Journal of neuroscience : the official journal of the Society for Neuroscience. 34(43):14403-19

Powell, C., Cornblath, E., Goldman, D. (2014) Zinc-binding Domain-dependent, Deaminase-independent Actions of Apolipoprotein B mRNA-editing Enzyme, Catalytic Polypeptide 2 (Apobec2), Mediate Its Effect on Zebrafish Retina Regeneration. The Journal of biological chemistry. 289(42):28924-41

Rajaram, K., Harding, R.L., Bailey, T., Patton, J.G., Hyde, D.R. (2014) Dynamic miRNA Expression Patterns During Retina Regeneration in Zebrafish: Reduced Dicer or miRNA Expression Suppresses Proliferation of Müller Glia-Derived Neuronal Progenitor Cells. Developmental Dynamics : an official publication of the American Association of Anatomists. 243(12):1591-605

Skaggs, K., Goldman, D., Parent, J.M. (2014) Excitotoxic brain injury in adult zebrafish stimulates neurogenesis and long-distance neuronal integration. Glia. 62(12):2061-79

Sun, L., Li, P., Carr, A.L., Gorsuch, R., Yarka, C., Li, J., Bartlett, M., Pfister, D., Hyde, D.R., and Li, L. (2014) Transcription of the SCL/TAL1 interrupting locus (Stil) is required for cell proliferation in adult zebrafish retinas. The Journal of biological chemistry. 289(10):6934-40

Zhao, X.F., Wan, J., Powell, C., Ramachandran, R., Myers, M.G., Goldman, D. (2014) Leptin and IL-6 Family Cytokines Synergize to Stimulate Müller Glia Reprogramming and Retina Regeneration. Cell Reports. 9(1):272-84

Nelson, C.M., Ackerman, K.M., O'Hayer, P., Bailey, T.J., Gorsuch, R.A., and Hyde, D.R. (2013) Tumor Necrosis Factor-Alpha Is Produced by Dying Retinal Neurons and Is Required for Muller Glia Proliferation during Zebrafish Retinal Regeneration. The Journal of neuroscience : the official journal of the Society for Neuroscience. 33(15):6524-6539

Powell, C., Grant, A.R., Cornblath, E., and Goldman, D. (2013) Analysis of DNA methylation reveals a partial reprogramming of the Muller glia genome during retina regeneration. Proceedings of the National Academy of Sciences of the United States of America. 110(49):19814-19819

Nelson, C.M., Gorsuch, R.A., Bailey, T.J., Ackerman, K.M., Kassen, S.C., and Hyde, D.R. (2012) Stat3 defines three populations of Müller glia and is required for initiating maximal Müller glia proliferation in the regenerating zebrafish retina. The Journal of comparative neurology. 520(18):4294-4311

Ramachandran, R., Zhao, X.F., and Goldman, D. (2012) Insm1a-mediated gene repression is essential for the formation and differentiation of Müller glia-derived progenitors in the injured retina. Nature cell biology. 14(10):1013-1023

Thomas, J.L., Nelson, C.M., Luo, X., Hyde, D.R., and Thummel, R. (2012) Characterization of multiple light damage paradigms reveals regional differences in photoreceptor loss. Experimental Eye Research. 97(1):105-116

Yin, J., Shine, L., Raycroft, F., Deeti, S., Reynolds, A., Ackerman, K.M., Glaviano, A., O'Farrell, S., O'Leary, O., Kilty, C., Kennedy, C., McLoughlin, S., Rice, M., Russell, E., Higgins, D.G., Hyde, D.R., and Kennedy, B.N. (2012) Inhibition of the pim1 oncogene results in diminished visual function. PLoS One. 7(12):e52177

Ramachandran, R., Zhao, X.F., and Goldman, D. (2011) Ascl1a/Dkk/ beta -catenin signaling pathway is necessary and glycogen synthase kinase-3 beta inhibition is sufficient for zebrafish retina regeneration. Proceedings of the National Academy of Sciences of the United States of America. 108(38):15858-63

Bailey, T.J., Fossum, S.L., Fimbel, S.M., Montgomery, J.E., and Hyde, D.R. (2010) The inhibitor of phagocytosis, O-phospho-L-serine, suppresses Müller glia proliferation and cone cell regeneration in the light-damaged zebrafish retina. Experimental Eye Research. 91(5):601-612

Ramachandran, R., Fausett, B.V., and Goldman, D. (2010) Ascl1a regulates Müller glia dedifferentiation and retinal regeneration through a Lin-28-dependent, let-7 microRNA signalling pathway. Nature cell biology. 12(11):1101-1107

Thummel, R., Kassen, S.C., Enright, J.M., Nelson, C.M., Montgomery, J.E., and Hyde, D.R. (2008) Characterization of Müller glia and neuronal progenitors during adult zebrafish retinal regeneration. Experimental Eye Research. 87(5):433-444

Thummel, R., Kassen, S.C., Montgomery, J.E., Enright, J.M., and Hyde, D.R. (2008) Inhibition of Müller glial cell division blocks regeneration of the light-damaged zebrafish retina. Developmental Neurobiology. 68(3):392-408

Fimbel, S.M., Montgomery, J.E., Burket, C.T., and Hyde, D.R. (2007) Regeneration of inner retinal neurons after intravitreal injection of ouabain in zebrafish. The Journal of neuroscience : the official journal of the Society for Neuroscience. 27(7):1712-1724

Kassen, S.C., Ramanan, V., Montgomery, J.E., Burket, C.T., Liu, C.G., Vihtelic, T.S., and Hyde, D.R. (2007) Time course analysis of gene expression during light-induced photoreceptor cell death and regeneration in albino zebrafish. Developmental Neurobiology. 67(8):1009-1031

Additional Citations (2):

ZFIN Staff (2015) Data Model Change: Sequence Targeting Reagents Removed from Environment. ZFIN Historical Data.

ZFIN Staff (2002) Scientific Curation. Manually curated data.