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ZFIN ID:
ZDB-GENE-130321-1
CITATIONS
(42 total)
Gene Name:
nanos homolog 2
Gene Symbol:
nanos2
Assis, L.H., Crespo, D., Morais, R.D., França, L.R., Bogerd, J., Schulz, R.W. (2016) INSL3 stimulates spermatogonial differentiation in testis of adult zebrafish (Danio rerio). Cell and tissue research. 363(2):579-88
Beer, R.L., and Draper, B.W. (2013) nanos3 maintains germline stem cells and expression of the conserved germline stem cell gene nanos2 in the zebrafish ovary. Developmental Biology. 374(2):308-318
Bertho, S., Clapp, M., Banisch, T.U., Bandemer, J., Raz, E., Marlow, F.L. (2021) Zebrafish
dazl
regulates cystogenesis and germline stem cell specification during the primordial germ cell to germline stem cell transition. Development (Cambridge, England). 148(7)
Cao, Z., Mao, X., Luo, L. (2019) Germline Stem Cells Drive Ovary Regeneration in Zebrafish. Cell Reports. 26:1709-1717.e3
Chen, Y., Tang, H., Wang, L., Wei, T., Liu, X., Lin, H. (2019) New insights into the role of mTORC1 in male fertility in zebrafish. General and comparative endocrinology. 286:113306
Crespo, D., Assis, L.H., Furmanek, T., Bogerd, J., Schulz, R.W. (2016) Expression profiling identifies Sertoli and Leydig cell genes as Fsh targets in adult zebrafish testis. Molecular and Cellular Endocrinology. 437:237-251
Crespo, D., Assis, L.H.C., van de Kant, H.J.G., de Waard, S., Safian, D., Lemos, M.S., Bogerd, J., Schulz, R.W. (2019) Endocrine and local signaling interact to regulate spermatogenesis in zebrafish: Follicle-stimulating hormone, retinoic acid and androgens. Development (Cambridge, England). 146(21):
Hartung, O., Forbes, M.M., Marlow, F.L. (2014) Zebrafish vasa is required for germ-cell differentiation and maintenance. Molecular reproduction and development. 81(10):946-61
Hayashi, M., Ichida, K., Sadaie, S., Miwa, M., Fujihara, R., Nagasaka, Y., Yoshizaki, G. (2019) Establishment of novel monoclonal antibodies for identification of type A spermatogonia in teleosts1. Biology of reproduction. 101(2):478-491
Islam, K.N., Ajao, A., Venkataramani, K., Rivera, J., Pathania, S., Henke, K., Siegfried, K.R. (2023) The RNA-binding protein Adad1 is necessary for germ cell maintenance and meiosis in zebrafish. PLoS Genetics. 19:e1010589e1010589
Kobayashi, M., Tani-Matsuhana, S., Ohkawa, Y., Sakamoto, H., Inoue, K. (2017) DND protein functions as a translation repressor during zebrafish embryogenesis. Biochemical and Biophysical Research Communications. 484(2):235-240
Li, N., Oakes, J.A., Storbeck, K., Cunliffe, V.T., Krone, N. (2019) The P450 side chain cleavage enzyme Cyp11a2 facilitates steroidogenesis in zebrafish. The Journal of endocrinology. 244(2):309-321
Li, X., Zhang, F., Wu, N., Ye, D., Wang, Y., Zhang, X., Sun, Y., Zhang, Y.A. (2020) A critical role of foxp3a-positive regulatory T cells in maintaining immune homeostasis in zebrafish testis development. Journal of genetics and genomics = Yi chuan xue bao. 47(9):547-561
Lin, Q., Mei, J., Li, Z., Zhang, X., Zhou, L., Gui, J.F. (2017) Distinct and Cooperative Roles of
amh
and
dmrt1
in Self-Renewal and Differentiation of Male Germ Cells in Zebrafish.. Genetics. 207(3):1007-1022
Liu, Y., Kassack, M.E., McFaul, M.E., Christensen, L.N., Siebert, S., Wyatt, S.R., Kamei, C.N., Horst, S., Arroyo, N., Drummond, I.A., Juliano, C.E., Draper, B.W. (2022) Single-cell transcriptome reveals insights into the development and function of the zebrafish ovary. eLIFE. 11:
Morais, R.D.V.S., Crespo, D., Nóbrega, R.H., Lemos, M.S., van de Kant, H.J.G., de França, L.R., Male, R., Bogerd, J., Schulz, R.W. (2017) Antagonistic regulation of spermatogonial differentiation in zebrafish (Danio rerio) by Igf3 and Amh. Molecular and Cellular Endocrinology. 454:112-124
Na, H., Park, J., Jeon, H., Jin, S., Choe, C.P. (2021) Pharyngeal endoderm expression of nanos1 is dispensable for craniofacial development. Gene expression patterns : GEP. 41:119202
Oakes, J.A., Barnard, L., Storbeck, K.H., Cunliffe, V.T., Krone, N.P. (2020) 11β-hydroxylase loss disrupts steroidogenesis and reproductive function in zebrafish. The Journal of endocrinology. 247(2):197-212
Oakes, J.A., Li, N., Wistow, B.R.C., Griffin, A., Barnard, L., Storbeck, K.H., Cunliffe, V.T., Krone, N.P. (2019) Ferredoxin 1b deficiency leads to testis disorganization, impaired spermatogenesis and feminization in zebrafish. Endocrinology. 160(10):2401-2416
Ramachandran, D., Sharma, K., Saxena, V., Nipu, N., Rajapaksha, D.C., Mennigen, J.A. (2023) Knock-out of vasotocin reduces reproductive success in female zebrafish,
Danio rerio
. Frontiers in endocrinology. 14:11512991151299
Rodrigues, M.S., Tovo-Neto, A., Rosa, I.F., Doretto, L.B., Fallah, H.P., Habibi, H.R., Nóbrega, R.H. (2022) Thyroid Hormones Deficiency Impairs Male Germ Cell Development: A Cross Talk Between Hypothalamic-Pituitary-Thyroid, and-Gonadal Axes in Zebrafish. Frontiers in cell and developmental biology. 10:865948
Safian, D., Bogerd, J., Schulz, R. (2018) Igf3 activates β-catenin signaling to stimulate spermatogonial differentiation in zebrafish. The Journal of endocrinology. 238(3):245-257
Safian, D., Morais, R.D., Bogerd, J., Schulz, R.W. (2016) Igf binding proteins protect undifferentiated spermatogonia in the zebrafish testis against excessive differentiation. Endocrinology. 157(11):4423-4433
Safian, D., Ryane, N., Bogerd, J., Schulz, R.W. (2018) Fsh stimulates Leydig cell Wnt5a production, enriching zebrafish type A spermatogonia. The Journal of endocrinology. 239:351-363
Shimizu, N., Matsuda, M. (2018) Identification of a Novel Zebrafish Mutant Line that Develops Testicular Germ Cell Tumors. Zebrafish. 16(1):15-28
Tang, H., Chen, Y., Wang, L., Yin, Y., Li, G., Guo, Y., Liu, Y., Lin, H., Cheng, C.H.K., Liu, X. (2017) Fertility impairment with defective spermatogenesis and steroidogenesis in male zebrafish lacking androgen receptor. Biology of reproduction. 98(2):227-238
Wang, X., Zhu, J., Wang, H., Deng, W., Jiao, S., Wang, Y., He, M., Zhang, F., Liu, T., Hao, Y., Ye, D., Sun, Y. (2023) Induced formation of primordial germ cells from zebrafish blastomeres by germplasm factors. Nature communications. 14:79187918
Wang, Y., Ye, D., Zhang, F., Zhang, R., Zhu, J., Wang, H., He, M., Sun, Y. (2021) Cyp11a2 is essential for oocyte development and spermatogonial stem cell differentiation in zebrafish. Endocrinology. 163(2):
Zhang, R., Tu, Y.X., Ye, D., Gu, Z., Chen, Z.X., Sun, Y. (2022) A Germline-Specific Regulator of Mitochondrial Fusion is Required for Maintenance and Differentiation of Germline Stem and Progenitor Cells. Advanced science (Weinheim, Baden-Wurttemberg, Germany). 9(36):e2203631
Zhang, Y., Zhou, Y., Tang, Q., Hu, F., Feng, L., Shen, J., Huang, B. (2018) The protective effects of selenium-enriched spirulina on the reproductive system of male zebrafish (Danio rerio) exposed to beta-cypermethrin. Food & function. 9(11):5791-5804
Islam, K.N., Ajao, A., Venkataramani, K., Rivera, J., Pathania, S., Henke, K., Siegfried, K.R. (2023) The RNA-binding protein Adad1 is necessary for germ cell maintenance and meiosis in zebrafish. PLoS Genetics. 19:e1010589e1010589
Ramachandran, D., Sharma, K., Saxena, V., Nipu, N., Rajapaksha, D.C., Mennigen, J.A. (2023) Knock-out of vasotocin reduces reproductive success in female zebrafish,
Danio rerio
. Frontiers in endocrinology. 14:11512991151299
Wang, X., Zhu, J., Wang, H., Deng, W., Jiao, S., Wang, Y., He, M., Zhang, F., Liu, T., Hao, Y., Ye, D., Sun, Y. (2023) Induced formation of primordial germ cells from zebrafish blastomeres by germplasm factors. Nature communications. 14:79187918
Liu, Y., Kassack, M.E., McFaul, M.E., Christensen, L.N., Siebert, S., Wyatt, S.R., Kamei, C.N., Horst, S., Arroyo, N., Drummond, I.A., Juliano, C.E., Draper, B.W. (2022) Single-cell transcriptome reveals insights into the development and function of the zebrafish ovary. eLIFE. 11:
Rodrigues, M.S., Tovo-Neto, A., Rosa, I.F., Doretto, L.B., Fallah, H.P., Habibi, H.R., Nóbrega, R.H. (2022) Thyroid Hormones Deficiency Impairs Male Germ Cell Development: A Cross Talk Between Hypothalamic-Pituitary-Thyroid, and-Gonadal Axes in Zebrafish. Frontiers in cell and developmental biology. 10:865948
Zhang, R., Tu, Y.X., Ye, D., Gu, Z., Chen, Z.X., Sun, Y. (2022) A Germline-Specific Regulator of Mitochondrial Fusion is Required for Maintenance and Differentiation of Germline Stem and Progenitor Cells. Advanced science (Weinheim, Baden-Wurttemberg, Germany). 9(36):e2203631
Bertho, S., Clapp, M., Banisch, T.U., Bandemer, J., Raz, E., Marlow, F.L. (2021) Zebrafish
dazl
regulates cystogenesis and germline stem cell specification during the primordial germ cell to germline stem cell transition. Development (Cambridge, England). 148(7)
Na, H., Park, J., Jeon, H., Jin, S., Choe, C.P. (2021) Pharyngeal endoderm expression of nanos1 is dispensable for craniofacial development. Gene expression patterns : GEP. 41:119202
Wang, Y., Ye, D., Zhang, F., Zhang, R., Zhu, J., Wang, H., He, M., Sun, Y. (2021) Cyp11a2 is essential for oocyte development and spermatogonial stem cell differentiation in zebrafish. Endocrinology. 163(2):
Li, X., Zhang, F., Wu, N., Ye, D., Wang, Y., Zhang, X., Sun, Y., Zhang, Y.A. (2020) A critical role of foxp3a-positive regulatory T cells in maintaining immune homeostasis in zebrafish testis development. Journal of genetics and genomics = Yi chuan xue bao. 47(9):547-561
Oakes, J.A., Barnard, L., Storbeck, K.H., Cunliffe, V.T., Krone, N.P. (2020) 11β-hydroxylase loss disrupts steroidogenesis and reproductive function in zebrafish. The Journal of endocrinology. 247(2):197-212
Cao, Z., Mao, X., Luo, L. (2019) Germline Stem Cells Drive Ovary Regeneration in Zebrafish. Cell Reports. 26:1709-1717.e3
Chen, Y., Tang, H., Wang, L., Wei, T., Liu, X., Lin, H. (2019) New insights into the role of mTORC1 in male fertility in zebrafish. General and comparative endocrinology. 286:113306
Crespo, D., Assis, L.H.C., van de Kant, H.J.G., de Waard, S., Safian, D., Lemos, M.S., Bogerd, J., Schulz, R.W. (2019) Endocrine and local signaling interact to regulate spermatogenesis in zebrafish: Follicle-stimulating hormone, retinoic acid and androgens. Development (Cambridge, England). 146(21):
Hayashi, M., Ichida, K., Sadaie, S., Miwa, M., Fujihara, R., Nagasaka, Y., Yoshizaki, G. (2019) Establishment of novel monoclonal antibodies for identification of type A spermatogonia in teleosts1. Biology of reproduction. 101(2):478-491
Li, N., Oakes, J.A., Storbeck, K., Cunliffe, V.T., Krone, N. (2019) The P450 side chain cleavage enzyme Cyp11a2 facilitates steroidogenesis in zebrafish. The Journal of endocrinology. 244(2):309-321
Oakes, J.A., Li, N., Wistow, B.R.C., Griffin, A., Barnard, L., Storbeck, K.H., Cunliffe, V.T., Krone, N.P. (2019) Ferredoxin 1b deficiency leads to testis disorganization, impaired spermatogenesis and feminization in zebrafish. Endocrinology. 160(10):2401-2416
Safian, D., Bogerd, J., Schulz, R. (2018) Igf3 activates β-catenin signaling to stimulate spermatogonial differentiation in zebrafish. The Journal of endocrinology. 238(3):245-257
Safian, D., Ryane, N., Bogerd, J., Schulz, R.W. (2018) Fsh stimulates Leydig cell Wnt5a production, enriching zebrafish type A spermatogonia. The Journal of endocrinology. 239:351-363
Shimizu, N., Matsuda, M. (2018) Identification of a Novel Zebrafish Mutant Line that Develops Testicular Germ Cell Tumors. Zebrafish. 16(1):15-28
Zhang, Y., Zhou, Y., Tang, Q., Hu, F., Feng, L., Shen, J., Huang, B. (2018) The protective effects of selenium-enriched spirulina on the reproductive system of male zebrafish (Danio rerio) exposed to beta-cypermethrin. Food & function. 9(11):5791-5804
Kobayashi, M., Tani-Matsuhana, S., Ohkawa, Y., Sakamoto, H., Inoue, K. (2017) DND protein functions as a translation repressor during zebrafish embryogenesis. Biochemical and Biophysical Research Communications. 484(2):235-240
Lin, Q., Mei, J., Li, Z., Zhang, X., Zhou, L., Gui, J.F. (2017) Distinct and Cooperative Roles of
amh
and
dmrt1
in Self-Renewal and Differentiation of Male Germ Cells in Zebrafish.. Genetics. 207(3):1007-1022
Morais, R.D.V.S., Crespo, D., Nóbrega, R.H., Lemos, M.S., van de Kant, H.J.G., de França, L.R., Male, R., Bogerd, J., Schulz, R.W. (2017) Antagonistic regulation of spermatogonial differentiation in zebrafish (Danio rerio) by Igf3 and Amh. Molecular and Cellular Endocrinology. 454:112-124
Tang, H., Chen, Y., Wang, L., Yin, Y., Li, G., Guo, Y., Liu, Y., Lin, H., Cheng, C.H.K., Liu, X. (2017) Fertility impairment with defective spermatogenesis and steroidogenesis in male zebrafish lacking androgen receptor. Biology of reproduction. 98(2):227-238
Assis, L.H., Crespo, D., Morais, R.D., França, L.R., Bogerd, J., Schulz, R.W. (2016) INSL3 stimulates spermatogonial differentiation in testis of adult zebrafish (Danio rerio). Cell and tissue research. 363(2):579-88
Crespo, D., Assis, L.H., Furmanek, T., Bogerd, J., Schulz, R.W. (2016) Expression profiling identifies Sertoli and Leydig cell genes as Fsh targets in adult zebrafish testis. Molecular and Cellular Endocrinology. 437:237-251
Safian, D., Morais, R.D., Bogerd, J., Schulz, R.W. (2016) Igf binding proteins protect undifferentiated spermatogonia in the zebrafish testis against excessive differentiation. Endocrinology. 157(11):4423-4433
Hartung, O., Forbes, M.M., Marlow, F.L. (2014) Zebrafish vasa is required for germ-cell differentiation and maintenance. Molecular reproduction and development. 81(10):946-61
Beer, R.L., and Draper, B.W. (2013) nanos3 maintains germline stem cells and expression of the conserved germline stem cell gene nanos2 in the zebrafish ovary. Developmental Biology. 374(2):308-318
Additional Citations (12):
Gaudet, P., Livstone, M., Thomas, P., The Reference Genome Project (2010) Annotation inferences using phylogenetic trees. Automated Data Submission.
UniProt curators (2015) Electronic Gene Ontology annotations created by transferring manual GO annotations between related proteins based on shared sequence features.. Automated Data Submission.
UniProt-GOA (2011) Gene Ontology annotation based on the automatic assignment of UniProtKB Subcellular Location terms in UniProtKB/TrEMBL entries. Manually curated data.
ZFIN Staff (2024) Association of Ensembl transcripts with ZFIN genes. Semi-automated Curation.
ZFIN Staff (2006) Curation of Ensembl Database Links. Automated Data Submission.
ZFIN Staff (2002) Curation of NCBI Gene Data Via Shared RNA Sequence IDs. Automated Data Submission.
ZFIN Staff (2003) Curation of unpublished nucleotide sequence accession numbers. Manually curated data.
ZFIN Staff (2002) Gene Ontology Annotation Through Association of InterPro Records with GO Terms. Automated Data Submission.
ZFIN Staff (2002) Gene Ontology Annotation Through Association of UniProt Keywords with GO Terms. Automated Data Submission.
ZFIN Staff (2017) Curation of Alliance of Genome Resources Database Links. Automated Data Submission.
ZFIN Staff (2023) Automated Curation of UniProt Database Links. Automated Data Submission.
ZFIN Staff (2003) Curation of VEGA Database Links. Automated Data Submission.
ZFIN Staff (2024) Association of Ensembl transcripts with ZFIN genes. Semi-automated Curation.
ZFIN Staff (2023) Automated Curation of UniProt Database Links. Automated Data Submission.
ZFIN Staff (2017) Curation of Alliance of Genome Resources Database Links. Automated Data Submission.
UniProt curators (2015) Electronic Gene Ontology annotations created by transferring manual GO annotations between related proteins based on shared sequence features.. Automated Data Submission.
UniProt-GOA (2011) Gene Ontology annotation based on the automatic assignment of UniProtKB Subcellular Location terms in UniProtKB/TrEMBL entries. Manually curated data.
Gaudet, P., Livstone, M., Thomas, P., The Reference Genome Project (2010) Annotation inferences using phylogenetic trees. Automated Data Submission.
ZFIN Staff (2006) Curation of Ensembl Database Links. Automated Data Submission.
ZFIN Staff (2003) Curation of VEGA Database Links. Automated Data Submission.
ZFIN Staff (2003) Curation of unpublished nucleotide sequence accession numbers. Manually curated data.
ZFIN Staff (2002) Gene Ontology Annotation Through Association of UniProt Keywords with GO Terms. Automated Data Submission.
ZFIN Staff (2002) Curation of NCBI Gene Data Via Shared RNA Sequence IDs. Automated Data Submission.
ZFIN Staff (2002) Gene Ontology Annotation Through Association of InterPro Records with GO Terms. Automated Data Submission.
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