ZFIN

ZFIN ID: ZDB-GENE-060526-130

ZFIN ID: ZDB-GENE-060526-130

CITATIONS (54 total)

Gene Name:	latent transforming growth factor beta binding protein 3
Gene Symbol:	ltbp3

Robertson, R.A., Knight, H.G., Lipovsky, C., Edwards, H.E., Ren, J., Chi, N.C., Yelon, D. (2026) Hedgehog and Bmp signaling pathways play opposing roles during establishment of the cardiac inflow tract in zebrafish. Development (Cambridge, England). :

Sam, J., Torregroza, I., Evans, T. (2024) Gata6 functions in zebrafish endoderm to regulate late differentiating arterial pole cardiogenesis. Development (Cambridge, England). 151(17):

DeMoya, R.A., Forman-Rubinsky, R.E., Fontaine, D., Shin, J., Watkins, S.C., Lo, C.W., Tsang, M. (2023) Sin3a associated protein 130 kDa, sap130, plays an evolutionary conserved role in zebrafish heart development. Frontiers in cell and developmental biology. 11:11971091197109

Abrial, M., Basu, S., Huang, M., Butty, V., Schwertner, A., Jeffrey, S., Jordan, D., Burns, C.E., Burns, C.G. (2022) Latent TGFβ binding proteins 1 and 3 protect the larval zebrafish outflow tract from aneurysmal dilatation. Disease models & mechanisms. 15(3):

Derrick, C.J., Pollitt, E.J.G., Sevilla Uruchurtu, A.S., Hussein, F., Grierson, A.J., Noël, E.S. (2021) Lamb1a regulates atrial growth by limiting second heart field addition during zebrafish heart development. Development (Cambridge, England). 148(20)

Duong, T.B., Holowiecki, A., Waxman, J.S. (2021) Retinoic acid signaling restricts the size of the first heart field within the anterior lateral plate mesoderm. Developmental Biology. 473:119-129

Jing, Y., Ren, Y., Witzel, H.R., Dobreva, G. (2021) A BMP4-p38 MAPK signaling axis controls ISL1 protein stability and activity during cardiogenesis. Stem Cell Reports. 16(8):1894-1905

Holowiecki, A., Linstrum, K., Ravisankar, P., Chetal, K., Salomonis, N., Waxman, J.S. (2020) Pbx4 limits heart size and fosters arch artery formation through partitioning second heart field progenitors and restricting proliferation. Development (Cambridge, England). 147(5):

Mao, A., Zhang, M., Li, L., Liu, J., Ning, G., Cao, Y., Wang, Q. (2020) Pharyngeal pouches provide a niche microenvironment for arch artery progenitor specification. Development (Cambridge, England). 148(2):

Sam, J., Mercer, E.J., Torregroza, I., Banks, K.M., Evans, T. (2020) Specificity, redundancy and dosage thresholds among gata4/5/6 genes during zebrafish cardiogenesis. Biology Open. 9(6):

Yin, H.M., Yan, L.F., Liu, Q., Peng, Z., Zhang, C.Y., Xia, Y., Su, D., Gu, A.H., Zhou, Y. (2020) Activating transcription factor 3 coordinates differentiation of cardiac and hematopoietic progenitors by regulating glucose metabolism. Science advances. 6:eaay9466

Capasso, T.L., Li, B., Volek, H.J., Khalid, W., Rochon, E.R., Anbalagan, A., Herdman, C., Yost, H.J., Villanueva, F.S., Kim, K., Roman, B.L. (2019) BMP10-mediated ALK1 signaling is continuously required for vascular development and maintenance. Angiogenesis. 23(2):203-220

Song, Y.C., Dohn, T.E., Rydeen, A.B., Nechiporuk, A.V., Waxman, J.S. (2019) HDAC1-mediated repression of the retinoic acid-responsive gene ripply3 promotes second heart field development. PLoS Genetics. 15:e1008165

Yang, R.M., Tao, J., Zhan, M., Yuan, H., Wang, H.H., Chen, S.J., Zhu, C., de Thé, H., Zhou, J., Guo, Y., Zhu, J. (2019) TAMM41 is required for heart valve differentiation via regulation of PINK-PARK2 dependent mitophagy. Cell death and differentiation. 26(11):2430-2446

Gibb, N., Lazic, S., Yuan, X., Deshwar, A.R., Leslie, M., Wilson, M.D., Scott, I.C. (2018) Hey2 regulates the size of the cardiac progenitor pool during vertebrate heart development. Development (Cambridge, England). 145(22):

Abrial, M., Paffett-Lugassy, N., Jeffrey, S., Jordan, D., O'Loughlin, E., Frederick, C.J., Burns, C.G., Burns, C.E. (2017) TGF-β Signaling Is Necessary and Sufficient for Pharyngeal Arch Artery Angioblast Formation. Cell Reports. 20:973-983

Gays, D., Hess, C., Camporeale, A., Ala, U., Provero, P., Mosimann, C., Santoro, M.M. (2017) An exclusive cellular and molecular network governs intestinal smooth muscle cell differentiation in vertebrates. Development (Cambridge, England). 144(3):464-478

Mandal, A., Holowiecki, A., Song, Y.C., Waxman, J.S. (2017) Wnt signaling balances specification of the cardiac and pharyngeal muscle fields. Mechanisms of Development. 143:32-41

Meng, Z.Z., Liu, W., Xia, Y., Yin, H.M., Zhang, C.Y., Su, D., Yan, L.F., Gu, A.H., Zhou, Y. (2017) The pro-inflammatory signalling regulator Stat4 promotes vasculogenesis of great vessels derived from endothelial precursors. Nature communications. 8:14640

Ocaña, O.H., Coskun, H., Minguillón, C., Murawala, P., Tanaka, E.M., Galcerán, J., Muñoz-Chápuli, R., Nieto, M.A. (2017) A right-handed signalling pathway drives heart looping in vertebrates. Nature. 549:86-90

Witzel, H.R., Cheedipudi, S., Gao, R., Stainier, D.Y., Dobreva, G.D. (2017) Isl2b regulates anterior second heart field development in zebrafish. Scientific Reports. 7:41043

Jahangiri, L., Sharpe, M., Novikov, N., González-Rosa, J.M., Borikova, A., Nevis, K., Paffett-Lugassy, N., Zhao, L., Adams, M., Guner-Ataman, B., Burns, C.E., Burns, C.G. (2016) The AP-1 transcription factor component Fosl2 potentiates the rate of myocardial differentiation from the zebrafish second heart field. Development (Cambridge, England). 143:113-22

Moriyama, Y., Ito, F., Takeda, H., Yano, T., Okabe, M., Kuraku, S., Keeley, F.W., Koshiba-Takeuchi, K. (2016) Evolution of the fish heart by sub/neofunctionalization of an elastin gene. Nature communications. 7:1039710397

Rydeen, A.B., Waxman, J.S. (2016) Cyp26 Enzymes Facilitate Second Heart Field Progenitor Addition and Maintenance of Ventricular Integrity. PLoS Biology. 14:e2000504

Burrows, J.T., Pearson, B.J., Scott, I.C. (2015) An In Vivo Requirement for the Mediator Subunit Med14 in the Maintenance of Stem Cell Populations. Stem Cell Reports. 4(4):670-84

Cavanaugh, A.M., Huang, J., Chen, J.N. (2015) Two developmentally distinct populations of neural crest cells contribute to the zebrafish heart. Developmental Biology. 404(2):103-12

Kao, R.M., Rurik, J.G., Farr, G.H., Dong, X.R., Majesky, M.W., Maves, L. (2015) Pbx4 is Required for the Temporal Onset of Zebrafish Myocardial Differentiation. Journal of developmental biology. 3:93-111

Strate, I., Tessadori, F., Bakkers, J. (2015) Glypican4 promotes cardiac specification and differentiation by attenuating canonical Wnt and Bmp signaling. Development (Cambridge, England). 142:1767-76

Zeng, X.X., Yelon, D. (2014) Cadm4 Restricts the Production of Cardiac Outflow Tract Progenitor Cells. Cell Reports. 7(4):951-60

Guner-Ataman, B., Paffett-Lugassy, N., Adams, M.S., Nevis, K.R., Jahangiri, L., Obregon, P., Kikuchi, K., Poss, K.D., Burns, C.E., and Burns, C.G. (2013) Zebrafish second heart field development relies on progenitor specification in anterior lateral plate mesoderm and nkx2.5 function. Development (Cambridge, England). 140(6):1353-1363

Nevis, K., Obregon, P., Walsh, C., Guner-Ataman, B., Burns, C.G., and Burns, C.E. (2013) Tbx1 is required for second heart field proliferation in zebrafish. Developmental Dynamics : an official publication of the American Association of Anatomists. 242(5):540-549

Targoff, K.L., Colombo, S., George, V., Schell, T., Kim, S.H., Solnica-Krezel, L., and Yelon, D. (2013) Nkx genes are essential for maintenance of ventricular identity. Development (Cambridge, England). 140(20):4203-4213

Varshney, G.K., Lu, J., Gildea, D., Huang, H., Pei, W., Yang, Z., Huang, S.C., Schoenfeld, D.S., Pho, N., Casero, D., Hirase, T., Mosbrook-Davis, D.M., Zhang, S., Jao, L.E., Zhang, B., Woods, I.G., Zimmerman, S., Schier, A.F., Wolfsberg, T., Pellegrini, M., Burgess, S.M., and Lin, S. (2013) A large-scale zebrafish gene knockout resource for the genome-wide study of gene function. Genome research. 23(4):727-735

Opitz, R., Maquet, E., Huisken, J., Antonica, F., Trubiroha, A., Pottier, G., Janssens, V., and Costagliola, S. (2012) Transgenic zebrafish illuminate the dynamics of thyroid morphogenesis and its relationship to cardiovascular development. Developmental Biology. 372(2):203-216

Zhou, Y., Cashman, T.J., Nevis, K.R., Obregon, P., Carney, S.A., Liu, Y., Gu, A., Mosimann, C., Sondalle, S., Peterson, R.E., Heideman, W., Burns, C.E., and Burns, C.G. (2011) Latent TGF-β binding protein 3 identifies a second heart field in zebrafish. Nature. 474(7353):645-8

Wang, D., Jao, L.E., Zheng, N., Dolan, K., Ivey, J., Zonies, S., Wu, X., Wu, K., Yang, H., Meng, Q., Zhu, Z., Zhang, B., Lin, S., and Burgess, S.M. (2007) Efficient genome-wide mutagenesis of zebrafish genes by retroviral insertions. Proceedings of the National Academy of Sciences of the United States of America. 104(30):12428-12433

Additional Citations (18):

ZFIN Staff (2024) Association of Ensembl transcripts with ZFIN genes. Semi-automated Curation.

ZFIN Staff (2023) Curation of NCBI Gene Data Via Shared Ensembl IDs (Supplemental NCBI Load). Automated Data Submission.

ZFIN Staff (2023) Automated Curation of UniProt Database Links. Automated Data Submission.

ZFIN Staff (2022) Electronic Gene Ontology annotations created by ARBA machine learning models. Automated Data Submission.

ZFIN Staff (2019) Semi-automated association of ENSDARG and ENSDART identifiers with ZFIN genes and transcripts. Semi-automated Curation.

ZFIN Staff (2017) Curation of PANTHER Gene IDs. Automated Data Submission.

ZFIN Staff (2017) Curation of Alliance of Genome Resources Database Links. Automated Data Submission.

Busch-Nentwich, E., Kettleborough, R., Dooley, C. M., Scahill, C., Sealy, I., White, R., Herd, C., Mehroke, S., Wali, N., Carruthers, S., Hall, A., Collins, J., Gibbons, R., Pusztai, Z., Clark, R., and Stemple, D.L. (2013) Sanger Institute Zebrafish Mutation Project mutant data submission. ZFIN Direct Data Submission.

ZFIN Staff (2013) Semi-automated association of ENSDARG identifiers with ZFIN genes for the ZMP project. Semi-automated Curation.

Burgess, S., and Lin, S. (2012) Viral Insertion Mutants Overwrite Data. ZFIN Direct Data Submission.

Burgess, S., and Lin, S. (2011) Viral Insertion Mutants. ZFIN Direct Data Submission.

Gaudet, P., Livstone, M., Thomas, P., The Reference Genome Project (2010) Annotation inferences using phylogenetic trees. Automated Data Submission.

ZFIN Staff (2003) Curation of VEGA Database Links. Automated Data Submission.

ZFIN Staff (2003) Curation of orthology data. Manually curated data.

ZFIN Staff (2002) Gene Ontology Annotation Through Association of UniProt Keywords with GO Terms. Automated Data Submission.

ZFIN Staff (2002) Scientific Curation. Manually curated data.

ZFIN Staff (2002) Gene Ontology Annotation Through Association of InterPro Records with GO Terms. Automated Data Submission.

ZFIN Staff (2002) Curation of EMBL records. Automated Data Submission.