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ZFIN ID:
ZDB-GENE-050419-191
CITATIONS
(31 total)
Gene Name:
ALX homeobox 1
Gene Symbol:
alx1
Barske, L., Rataud, P., Behizad, K., Del Rio, L., Cox, S.G., Crump, J.G. (2018) Essential Role of Nr2f Nuclear Receptors in Patterning the Vertebrate Upper Jaw. Developmental Cell. 44(3):337-347.e5
Dee, C.T., Szymoniuk, C.R., Mills, P.E., and Takahashi, T. (2013) Defective Neural Crest Migration Revealed by a Zebrafish model of Alx1-Related Frontonasal Dysplasia. Human molecular genetics. 22(2):239-251
Diotel, N., Viales, R.R., Armant, O., März, M., Ferg, M., Rastegar, S., Strähle, U. (2015) Comprehensive expression map of transcription regulators in the adult zebrafish telencephalon reveals distinct neurogenic niches. The Journal of comparative neurology. 523(8):1202-21
Jang, H.S., Chen, Y., Ge, J., Wilkening, A.N., Hou, Y., Lee, H.J., Choi, Y.R., Lowdon, R.F., Xing, X., Li, D., Kaufman, C.K., Johnson, S.L., Wang, T. (2021) Epigenetic dynamics shaping melanophore and iridophore cell fate in zebrafish. Genome biology. 22:282
Jimenez, L., Wang, J., Morrison, M.A., Whatcott, C., Soh, K.K., Warner, S., Bearss, D., Jette, C.A., Stewart, R.A. (2016) Phenotypic chemical screening using zebrafish neural crest reporters identifies retinoid acid as an inhibitor of epithelial morphogenesis. Disease models & mechanisms. 9(4):389-400
Lukoseviciute, M., Gavriouchkina, D., Williams, R.M., Hochgreb-Hagele, T., Senanayake, U., Chong-Morrison, V., Thongjuea, S., Repapi, E., Mead, A., Sauka-Spengler, T. (2018) From Pioneer to Repressor: Bimodal foxd3 Activity Dynamically Remodels Neural Crest Regulatory Landscape In Vivo. Developmental Cell. 47:608-628.e6
McGonnell, I.M., Graham, A., Richardson, J., Fish, J.L., Depew, M.J., Dee, C.T., Holland, P.W., and Takahashi, T. (2011) Evolution of the Alx homeobox gene family: parallel retention and independent loss of the vertebrate Alx3 gene. Evolution & development. 13(4):353-351
Mitchell, J.M., Sucharov, J., Pulvino, A.T., Brooks, E.P., Gillen, A.E., Nichols, J.T. (2021) The
alx3
gene shapes the zebrafish neurocranium by regulating frontonasal neural crest cell differentiation timing. Development (Cambridge, England). 148(7):
Nguyen, T.T., Mitchell, J.M., Kiel, M.D., Kenny, C.P., Li, H., Jones, K.L., Cornell, R.A., Williams, T.J., Nichols, J.T., Van Otterloo, E. (2023) TFAP2 paralogs regulate midfacial development in part through a conserved ALX genetic pathway. Development (Cambridge, England). 151(1):
Pini, J., Kueper, J., Hu, Y.D., Kawasaki, K., Yeung, P., Tsimbal, C., Yoon, B., Carmichael, N., Maas, R.L., Cotney, J., Grinblat, Y., Liao, E.C. (2020) ALX1-related frontonasal dysplasia results from defective neural crest cell development and migration. EMBO Molecular Medicine. 12(10):e12013
Sedykh, I., Yoon, B., Roberson, L., Moskvin, O., Dewey, C.N., Grinblat, Y. (2017) Zebrafish zic2 controls formation of periocular neural crest and choroid fissure morphogenesis. Developmental Biology. 429(1):92-104
Sharma, P., MacLean, A.L., Meinecke, L., Clouthier, D., Nie, Q., Schilling, T.F. (2018) Transcriptomics reveals complex kinetics of dorsal-ventral patterning gene expression in the mandibular arch. Genesis (New York, N.Y. : 2000). 57(1):e23275
Wang, H., Holland, P.W.H., Takahashi, T. (2019) Gene profiling of head mesoderm in early zebrafish development: insights into the evolution of cranial mesoderm. EvoDevo. 10:14
Yoon, B., Yeung, P., Santistevan, N., Bluhm, L., Kawasaki, K., Kueper, J., Dubielzig, R., Vanoudenhove, J., Cotney, J., Liao, E.C., Grinblat, Y. (2022) Zebrafish models of Alx-linked frontonasal dysplasia reveal a role for Alx1 and Alx3 in the anterior segment and vasculature of the developing eye. Biology Open. 11(5):
Nguyen, T.T., Mitchell, J.M., Kiel, M.D., Kenny, C.P., Li, H., Jones, K.L., Cornell, R.A., Williams, T.J., Nichols, J.T., Van Otterloo, E. (2023) TFAP2 paralogs regulate midfacial development in part through a conserved ALX genetic pathway. Development (Cambridge, England). 151(1):
Yoon, B., Yeung, P., Santistevan, N., Bluhm, L., Kawasaki, K., Kueper, J., Dubielzig, R., Vanoudenhove, J., Cotney, J., Liao, E.C., Grinblat, Y. (2022) Zebrafish models of Alx-linked frontonasal dysplasia reveal a role for Alx1 and Alx3 in the anterior segment and vasculature of the developing eye. Biology Open. 11(5):
Jang, H.S., Chen, Y., Ge, J., Wilkening, A.N., Hou, Y., Lee, H.J., Choi, Y.R., Lowdon, R.F., Xing, X., Li, D., Kaufman, C.K., Johnson, S.L., Wang, T. (2021) Epigenetic dynamics shaping melanophore and iridophore cell fate in zebrafish. Genome biology. 22:282
Mitchell, J.M., Sucharov, J., Pulvino, A.T., Brooks, E.P., Gillen, A.E., Nichols, J.T. (2021) The
alx3
gene shapes the zebrafish neurocranium by regulating frontonasal neural crest cell differentiation timing. Development (Cambridge, England). 148(7):
Pini, J., Kueper, J., Hu, Y.D., Kawasaki, K., Yeung, P., Tsimbal, C., Yoon, B., Carmichael, N., Maas, R.L., Cotney, J., Grinblat, Y., Liao, E.C. (2020) ALX1-related frontonasal dysplasia results from defective neural crest cell development and migration. EMBO Molecular Medicine. 12(10):e12013
Wang, H., Holland, P.W.H., Takahashi, T. (2019) Gene profiling of head mesoderm in early zebrafish development: insights into the evolution of cranial mesoderm. EvoDevo. 10:14
Barske, L., Rataud, P., Behizad, K., Del Rio, L., Cox, S.G., Crump, J.G. (2018) Essential Role of Nr2f Nuclear Receptors in Patterning the Vertebrate Upper Jaw. Developmental Cell. 44(3):337-347.e5
Lukoseviciute, M., Gavriouchkina, D., Williams, R.M., Hochgreb-Hagele, T., Senanayake, U., Chong-Morrison, V., Thongjuea, S., Repapi, E., Mead, A., Sauka-Spengler, T. (2018) From Pioneer to Repressor: Bimodal foxd3 Activity Dynamically Remodels Neural Crest Regulatory Landscape In Vivo. Developmental Cell. 47:608-628.e6
Sharma, P., MacLean, A.L., Meinecke, L., Clouthier, D., Nie, Q., Schilling, T.F. (2018) Transcriptomics reveals complex kinetics of dorsal-ventral patterning gene expression in the mandibular arch. Genesis (New York, N.Y. : 2000). 57(1):e23275
Sedykh, I., Yoon, B., Roberson, L., Moskvin, O., Dewey, C.N., Grinblat, Y. (2017) Zebrafish zic2 controls formation of periocular neural crest and choroid fissure morphogenesis. Developmental Biology. 429(1):92-104
Jimenez, L., Wang, J., Morrison, M.A., Whatcott, C., Soh, K.K., Warner, S., Bearss, D., Jette, C.A., Stewart, R.A. (2016) Phenotypic chemical screening using zebrafish neural crest reporters identifies retinoid acid as an inhibitor of epithelial morphogenesis. Disease models & mechanisms. 9(4):389-400
Diotel, N., Viales, R.R., Armant, O., März, M., Ferg, M., Rastegar, S., Strähle, U. (2015) Comprehensive expression map of transcription regulators in the adult zebrafish telencephalon reveals distinct neurogenic niches. The Journal of comparative neurology. 523(8):1202-21
Dee, C.T., Szymoniuk, C.R., Mills, P.E., and Takahashi, T. (2013) Defective Neural Crest Migration Revealed by a Zebrafish model of Alx1-Related Frontonasal Dysplasia. Human molecular genetics. 22(2):239-251
McGonnell, I.M., Graham, A., Richardson, J., Fish, J.L., Depew, M.J., Dee, C.T., Holland, P.W., and Takahashi, T. (2011) Evolution of the Alx homeobox gene family: parallel retention and independent loss of the vertebrate Alx3 gene. Evolution & development. 13(4):353-351
Additional Citations (17):
Gaudet, P., Livstone, M., Thomas, P., The Reference Genome Project (2010) Annotation inferences using phylogenetic trees. Automated Data Submission.
GOA, HGNC, AgBase and UniProtKB curators (2007) Manual transfer of experimentally-verified manual GO annotation data to orthologs by curator judgment of sequence similarity. ZFIN Direct Data Submission.
UniProt-GOA (2011) Gene Ontology annotation based on the automatic assignment of UniProtKB Subcellular Location terms in UniProtKB/TrEMBL entries. Manually curated data.
Zebrafish Nomenclature Committee (2018) Nomenclature Data Curation (2018). Nomenclature Committee Submission.
ZFIN Staff (2019) Semi-automated association of ENSDARG and ENSDART identifiers with ZFIN genes and transcripts. Semi-automated Curation.
ZFIN Staff (2002) Curation of EMBL records. Automated Data Submission.
ZFIN Staff (2013) Semi-automated association of ENSDARG identifiers with ZFIN genes for the ZMP project. Semi-automated Curation.
ZFIN Staff (2023) Curation of NCBI Gene Data Via Shared Ensembl IDs (Supplemental NCBI Load). Automated Data Submission.
ZFIN Staff (2003) Curation of orthology data. Manually curated data.
ZFIN Staff (2002) Gene Ontology Annotation Through Association of InterPro Records with GO Terms. Automated Data Submission.
ZFIN Staff (2002) Gene Ontology Annotation Through Association of UniProt Keywords with GO Terms. Automated Data Submission.
ZFIN Staff (2017) Curation of Alliance of Genome Resources Database Links. Automated Data Submission.
ZFIN Staff (2023) Automated Curation of UniProt Database Links. Automated Data Submission.
ZFIN Staff (2017) Curation of PANTHER Gene IDs. Automated Data Submission.
ZFIN Staff (2020) Addition of links from ZFIN to Expression Atlas. Semi-automated Curation.
ZFIN Staff (2013) Curation of NCBI Gene Data Via Shared Vega Gene IDs. Automated Data Submission.
ZFIN Staff (2003) Curation of VEGA Database Links. Automated Data Submission.
ZFIN Staff (2023) Curation of NCBI Gene Data Via Shared Ensembl IDs (Supplemental NCBI Load). Automated Data Submission.
ZFIN Staff (2023) Automated Curation of UniProt Database Links. Automated Data Submission.
ZFIN Staff (2020) Addition of links from ZFIN to Expression Atlas. Semi-automated Curation.
ZFIN Staff (2019) Semi-automated association of ENSDARG and ENSDART identifiers with ZFIN genes and transcripts. Semi-automated Curation.
Zebrafish Nomenclature Committee (2018) Nomenclature Data Curation (2018). Nomenclature Committee Submission.
ZFIN Staff (2017) Curation of PANTHER Gene IDs. Automated Data Submission.
ZFIN Staff (2017) Curation of Alliance of Genome Resources Database Links. Automated Data Submission.
ZFIN Staff (2013) Semi-automated association of ENSDARG identifiers with ZFIN genes for the ZMP project. Semi-automated Curation.
ZFIN Staff (2013) Curation of NCBI Gene Data Via Shared Vega Gene IDs. Automated Data Submission.
UniProt-GOA (2011) Gene Ontology annotation based on the automatic assignment of UniProtKB Subcellular Location terms in UniProtKB/TrEMBL entries. Manually curated data.
Gaudet, P., Livstone, M., Thomas, P., The Reference Genome Project (2010) Annotation inferences using phylogenetic trees. Automated Data Submission.
GOA, HGNC, AgBase and UniProtKB curators (2007) Manual transfer of experimentally-verified manual GO annotation data to orthologs by curator judgment of sequence similarity. ZFIN Direct Data Submission.
ZFIN Staff (2003) Curation of VEGA Database Links. Automated Data Submission.
ZFIN Staff (2003) Curation of orthology data. Manually curated data.
ZFIN Staff (2002) Gene Ontology Annotation Through Association of UniProt Keywords with GO Terms. Automated Data Submission.
ZFIN Staff (2002) Gene Ontology Annotation Through Association of InterPro Records with GO Terms. Automated Data Submission.
ZFIN Staff (2002) Curation of EMBL records. Automated Data Submission.
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