ZFIN

ZFIN ID: ZDB-GENE-041111-215

CITATIONS (27 total)

Gene Name:	methylenetetrahydrofolate reductase (NAD(P)H)
Gene Symbol:	mthfr

Liang, S., Zhang, H., Jiao, L., Shao, R., Lan, Y., Liao, X., Mai, K., Ai, Q., Wan, M. (2024) Vitamin D promotes the folate transport and metabolism in zebrafish (Danio rerio). American journal of physiology. Endocrinology and metabolism. 326(4):E482-E492

Simonian, R., Pannia, E., Hammoud, R., Noche, R.R., Cui, X., Kranenburg, E., Kubant, R., Ashcraft, P., Wasek, B., Bottiglieri, T., Dowling, J.J., Anderson, G.H. (2023) Methylenetetrahydrofolate reductase deficiency and high dose FA supplementation disrupt embryonic development of energy balance and metabolic homeostasis in zebrafish. Human molecular genetics. 32(9):1575-1588

Han, X., Wang, B., Jin, D., Liu, K., Wang, H., Chen, L., Zu, Y. (2021) Precise Dose of Folic Acid Supplementation Is Essential for Embryonic Heart Development in Zebrafish. Biology. 11(1):

Hsiao, T.H., Lee, G.H., Chang, Y.S., Chen, B.H., Fu, T.F. (2021) The Incoherent Fluctuation of Folate Pools and Differential Regulation of Folate Enzymes Prioritize Nucleotide Supply in the Zebrafish Model Displaying Folate Deficiency-Induced Microphthalmia and Visual Defects. Frontiers in cell and developmental biology. 9:702969

Liu, L.Y., Alexa, K., Cortes, M., Schatzman-Bone, S., Kim, A.J., Mukhopadhyay, B., Cinar, R., Kunos, G., North, T.E., Goessling, W. (2016) Cannabinoid receptor signaling regulates liver development and metabolism. Development (Cambridge, England). 143:609-22

Elkon, R., Milon, B., Morrison, L., Shah, M., Vijayakumar, S., Racherla, M., Leitch, C.C., Silipino, L., Hadi, S., Weiss-Gayet, M., Barras, E., Schmid, C.D., Ait-Lounis, A., Barnes, A., Song, Y., Eisenman, D.J., Eliyahu, E., Frolenkov, G.I., Strome, S.E., Durand, B., Zaghloul, N.A., Jones, S.M., Reith, W., Hertzano, R. (2015) RFX transcription factors are essential for hearing in mice. Nature communications. 6:8549

Lee, M.S., Bonner, J.R., Bernard, D.J., Sanchez, E.L., Sause, E.T., Prentice, R.R., Burgess, S.M., and Brody, L.C. (2012) Disruption of the folate pathway in zebrafish causes developmental defects. BMC Developmental Biology. 12(1):12

Additional Citations (20):

ZFIN Staff (2024) Association of Ensembl transcripts with ZFIN genes. Semi-automated Curation.

ZFIN Staff (2023) Automated Curation of UniProt Database Links. Automated Data Submission.

ZFIN Staff (2022) Electronic Gene Ontology annotations created by ARBA machine learning models. Automated Data Submission.

ZFIN Staff (2020) Addition of links from ZFIN to Expression Atlas. Semi-automated Curation.

ZFIN Staff (2017) Curation of PANTHER Gene IDs. Automated Data Submission.

ZFIN Staff (2017) Curation of Alliance of Genome Resources Database Links. Automated Data Submission.

ZFIN Staff (2013) Semi-automated association of ENSDARG identifiers with ZFIN genes for the ZMP project. Semi-automated Curation.

UniProt-GOA (2012) Gene Ontology annotation based on UniPathway vocabulary mapping. Manually curated data.

Gaudet, P., Livstone, M., Thomas, P., The Reference Genome Project (2010) Annotation inferences using phylogenetic trees. Automated Data Submission.

ZFIN Staff (2007) Microarray Expression to Gene Association in ZFIN. Semi-automated Curation.

ZFIN Staff (2006) Curation of Ensembl Database Links. Automated Data Submission.

Thisse, B., Thisse, C. (2004) Fast Release Clones: A High Throughput Expression Analysis. ZFIN Direct Data Submission.

Zebrafish Nomenclature Committee (2003) Nomenclature Data Curation (2003-2010). Nomenclature Committee Submission.

ZFIN Staff (2003) Curation of VEGA Database Links. Automated Data Submission.

ZFIN Staff (2003) Curation of orthology data. Manually curated data.

ZFIN Staff (2003) Gene Ontology Annotation Through Association of Enzyme Commission numbers with GO Terms. Automated Data Submission.

ZFIN Staff (2002) Gene Ontology Annotation Through Association of UniProt Keywords with GO Terms. Automated Data Submission.

ZFIN Staff (2002) Curation of NCBI Gene Data Via Shared RNA Sequence IDs. Automated Data Submission.

ZFIN Staff (2002) Scientific Curation. Manually curated data.

ZFIN Staff (2002) Gene Ontology Annotation Through Association of InterPro Records with GO Terms. Automated Data Submission.