ZFIN

ZFIN ID: ZDB-GENE-040426-2232

ZFIN ID: ZDB-GENE-040426-2232

CITATIONS (38 total)

Gene Name:	microtubule-associated protein 1 light chain 3 alpha
Gene Symbol:	map1lc3a

Della Vecchia, S., Imbrici, P., Liantonio, A., Naef, V., Damiani, D., Licitra, R., Bernardi, S., Marchese, M., Santorelli, F.M. (2025) Dapagliflozin ameliorates Lafora disease phenotype in a zebrafish model. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie. 183:117800117800

Gao, X., Zhang, J., Lin, Y., Tian, K., Tu, J., Wu, Z., Lv, X., Hu, H., Liu, X., Lin, S., Zhu, A. (2025) Periplocin and bufalin induce cardiotoxicity by regulating AMPK/SIRT1/PGC-1α pathway to inhibit energy metabolism and trigger autophagy. Phytomedicine : international journal of phytotherapy and phytopharmacology. 150:157688157688

Marchese, M., Bernardi, S., Vivarelli, R., Doccini, S., Santucci, L., Ogi, A., Licitra, R., Zang, J., Soliymani, R., Mero, S., Neuhauss, S.C., Ciarmoli, L., Signore, G., Lalowski, M.M., Santorelli, F.M. (2025) CLN5 deficiency impairs glucose uptake and uncovers PHGDH as a potential biomarker in Batten disease. Molecular psychiatry. :

Sun, C.C., Chen, Z.L., Yang, D., Xiao, J.L., Chen, X.T., Peng, X.Y., Wu, X.S., Tang, C.F. (2025) Loss of popdc3 Impairs Mitochondrial Function and Causes Skeletal Muscle Atrophy and Reduced Swimming Ability in Zebrafish. Journal of cachexia, sarcopenia and muscle. 16:e13794e13794

Li, J., Zhang, Y., Zuo, Z., Zhang, Z., Wang, Y., Chang, S., Huang, J., Dai, Y., Ge, J. (2024) Salvianolate injection ameliorates cardiomyopathy by regulating autophagic flux through miR-30a/becn1 axis in zebrafish. Chinese Medical Journal. :

Marchese, M., Bernardi, S., Ogi, A., Licitra, R., Silvi, G., Mero, S., Galatolo, D., Gammaldi, N., Doccini, S., Ratto, G.M., Rapposelli, S., Neuhauss, S.C.F., Zang, J., Rocchiccioli, S., Michelucci, E., Ceccherini, E., Santorelli, F.M. (2024) Targeting autophagy impairment improves the phenotype of a novel CLN8 zebrafish model. Neurobiology of disease. 197:106536

Fung, C., Wilding, B., Schittenhelm, R.B., Bryson-Richardson, R.J., Bird, P.I. (2023) Expression of the Z Variant of α1-Antitrypsin Suppresses Hepatic Cholesterol Biosynthesis in Transgenic Zebrafish. International Journal of Molecular Sciences. 24(3):

Della Vecchia, S., Ogi, A., Licitra, R., Abramo, F., Nardi, G., Mero, S., Landi, S., Battini, R., Sicca, F., Ratto, G.M., Santorelli, F.M., Marchese, M. (2022) Trehalose Treatment in Zebrafish Model of Lafora Disease. International Journal of Molecular Sciences. 23(12)

Li, L., Chen, M., Liu, W., Tai, P., Liu, X., Liu, J.X. (2022) Zebrafish cox17 modulates primitive erythropoiesis via regulation of mitochondrial metabolism to facilitate hypoxia tolerance. FASEB journal : official publication of the Federation of American Societies for Experimental Biology. 36:e22596

Wen, W., Sun, C., Chen, Z., Yang, D., Zhou, Z., Peng, X., Tang, C. (2022) Alcohol Induces Zebrafish Skeletal Muscle Atrophy through HMGB1/TLR4/NF-κB Signaling. Life (Basel, Switzerland). 12(8)

Castillo-Castellanos, F., Ramírez, L., Lomelí, H. (2021) zmiz1a zebrafish mutants have defective erythropoiesis, altered expression of autophagy genes, and a deficient response to vitamin D. Life sciences. 284:119900

Sun, C.C., Zhou, Z.Q., Chen, Z.L., Zhu, R.K., Yang, D., Peng, X.Y., Zheng, L., Tang, C.F. (2021) Identification of Potentially Related Genes and Mechanisms Involved in Skeletal Muscle Atrophy Induced by Excessive Exercise in Zebrafish. Biology. 10(8):

Bello-Perez, M., Pereiro, P., Coll, J., Novoa, B., Perez, L., Falco, A. (2020) Zebrafish C-reactive protein isoforms inhibit SVCV replication by blocking autophagy through interactions with cell membrane cholesterol. Scientific Reports. 10:566

González-Rodríguez, P., Cheray, M., Füllgrabe, J., Salli, M., Engskog-Vlachos, P., Keane, L., Cunha, V., Lupa, A., Li, W., Ma, Q., Dreij, K., Rosenfeld, M.G., Joseph, B. (2020) The DNA methyltransferase DNMT3A contributes to autophagy long-term memory. Autophagy. 17(5):1259-1277

Zhao, C., Wang, M., Jia, Z., Li, E., Zhao, X., Li, F., Lin, R. (2019) Similar hepatotoxicity response induced by Rhizoma Paridis in zebrafish larvae, cell and rat. Journal of ethnopharmacology. 250:112440

Pan, Y.X., Luo, Z., Zhuo, M.Q., Wei, C.C., Chen, G.H., Song, Y.F. (2018) Oxidative stress and mitochondrial dysfunction mediated Cd-induced hepatic lipid accumulation in zebrafish Danio rerio. Aquatic toxicology (Amsterdam, Netherlands). 199:12-20

Bayés, À., Collins, M.O., Reig-Viader, R., Gou, G., Goulding, D., Izquierdo, A., Choudhary, J.S., Emes, R.D., Grant, S.G. (2017) Evolution of complexity in the zebrafish synapse proteome. Nature communications. 8:14613

Slade, L., Cowie, A., Martynuik, C.J., Kienesberger, P.C., Pulinilkunnil, T. (2017) Dieldrin Augments mTOR Signaling and Regulates Genes Associated with Cardiovascular Disease in the Adult Zebrafish Heart (Danio rerio).. The Journal of pharmacology and experimental therapeutics. 361(3):375-385

Elkon, R., Milon, B., Morrison, L., Shah, M., Vijayakumar, S., Racherla, M., Leitch, C.C., Silipino, L., Hadi, S., Weiss-Gayet, M., Barras, E., Schmid, C.D., Ait-Lounis, A., Barnes, A., Song, Y., Eisenman, D.J., Eliyahu, E., Frolenkov, G.I., Strome, S.E., Durand, B., Zaghloul, N.A., Jones, S.M., Reith, W., Hertzano, R. (2015) RFX transcription factors are essential for hearing in mice. Nature communications. 6:8549

Ganesan, S., Moussavi Nik, S.H., Newman, M., Lardelli, M. (2014) Identification and expression analysis of the zebrafish orthologues of mammalian MAP1LC3 gene family. Experimental cell research. 328(1):228-37

Yabu, T., Imamura, S., Mizusawa, N., Touhata, K., and Yamashita, M. (2012) Induction of Autophagy by Amino Acid Starvation in Fish Cells. Marine biotechnology (New York, N.Y.). 14(4):491-501

Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G., Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D., Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K., Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F., Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L., Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L., Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S., Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J., Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J., McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S., Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W., Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A., Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S., Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y., Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D., Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M., Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E., Schnerch,A., Schein,J.E., Jones,S.J., and Marra,M.A. (2002) Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Proceedings of the National Academy of Sciences of the United States of America. 99(26):16899-903

Additional Citations (16):

ZFIN Staff (2023) Automated Curation of UniProt Database Links. Automated Data Submission.

ZFIN Staff (2022) Electronic Gene Ontology annotations created by ARBA machine learning models. Automated Data Submission.

ZFIN Staff (2020) Addition of links from ZFIN to Expression Atlas. Semi-automated Curation.

ZFIN Staff (2017) Curation of PANTHER Gene IDs. Automated Data Submission.

ZFIN Staff (2017) Curation of Alliance of Genome Resources Database Links. Automated Data Submission.

ZFIN Staff (2013) Semi-automated association of ENSDARG identifiers with ZFIN genes for the ZMP project. Semi-automated Curation.

UniProt-GOA (2011) Gene Ontology annotation based on the automatic assignment of UniProtKB Subcellular Location terms in UniProtKB/TrEMBL entries. Manually curated data.

Gaudet, P., Livstone, M., Thomas, P., The Reference Genome Project (2010) Annotation inferences using phylogenetic trees. Automated Data Submission.

ZFIN Staff (2007) Microarray Expression to Gene Association in ZFIN. Semi-automated Curation.

ZFIN Staff (2006) Curation of Ensembl Database Links. Automated Data Submission.

Thisse, B., Thisse, C. (2004) Fast Release Clones: A High Throughput Expression Analysis. ZFIN Direct Data Submission.

ZFIN Staff (2004) ZGC Data Curation and Association in ZFIN by ZFIN Staff. Semi-automated Curation.

ZFIN Staff (2003) Curation of VEGA Database Links. Automated Data Submission.

ZFIN Staff (2003) Curation of orthology data. Manually curated data.

ZFIN Staff (2002) Gene Ontology Annotation Through Association of UniProt Keywords with GO Terms. Automated Data Submission.

ZFIN Staff (2002) Curation of NCBI Gene Data Via Shared RNA Sequence IDs. Automated Data Submission.