ZFIN Phenotype Figure Summary for Marker vma21

Phenotype Figure Summary

Marker:	vma21
Conditions:	Standard or Control

Publication	Data	Fish	Anatomy
Huang et al., 2025	Figure 1	vma21^{hsc228/hsc228} (TU) , vma21^{hsc227/hsc227} (TU)	whole organism Ab1-vma21 labeling decreased amount, abnormal
	Figure 2	vma21^hsc227/+; vma21^hsc228/+ (TU) , vma21^{hsc228/hsc228} (TU) , vma21^{hsc227/hsc227} (TU)	melanocyte decreased distribution, abnormal swim bladder uninflated, abnormal swimming behavior decreased process quality, abnormal whole organism dead, abnormal whole organism decreased length, abnormal xanthophore decreased distribution, abnormal
	Figure 3	vma21^{hsc228/hsc228} (TU) , vma21^{hsc227/hsc227} (TU)	muscle lysosomal lumen acidification decreased process quality, abnormal muscle lysosome Ab2-lamp1 labeling decreased amount, abnormal muscle lysosome organization decreased process quality, abnormal
	Figure 4	vma21^hsc227/+; vma21^hsc228/+ (TU) , vma21^{hsc228/hsc228} (TU) , vma21^{hsc227/hsc227} (TU)	muscle vacuole increased amount, abnormal whole organism Ab6-map1lc3b labeling increased amount, abnormal
	Figure 5	hsc229Tg + CRISPR2-vma21 + CRISPR3-vma21 + CRISPR4-vma21 (TU) , vma21^{hsc227/hsc227} (TU)	gall bladder bile decreased amount, abnormal liver decreased size, abnormal liver lipid droplet increased amount, abnormal
	Figure 6	vma21^{hsc228/hsc228} (TU)	gall bladder bile decreased amount, abnormal muscle cell disorganized, abnormal thigmotaxis decreased process quality, abnormal whole organism dead, abnormal