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Phenotype Figure Summary
Marker:
cacnb2a
Conditions:
Standard or Control
Publication
Data
Fish
Anatomy
Charlton-Perkins
et al.
, 2019
Figure S2
mi2001Tg + CRISPR10-cacnb2a + CRISPR1-cacnb2a
Muller cell cell body position, abnormal
Muller cell cell body spatial pattern, abnormal
Muller cell physical object quality, abnormal
Table S4
mi2001Tg + CRISPR10-cacnb2a + CRISPR1-cacnb2a
Muller cell glial cell projection overlap with Muller cell glial cell projection, abnormal
Muller cell physical object quality, abnormal
Thyme
et al.
, 2019
Fig. S4
cacnb2a
a246/a246
habituation decreased rate, abnormal
prepulse inhibition decreased magnitude, abnormal
response to absence of light decreased process quality, abnormal
startle response decreased magnitude, abnormal
swimming decreased frequency, abnormal
swimming increased linear velocity, abnormal
swimming increased occurrence, abnormal
swimming increased spatial extent of a process, abnormal
Chernyavskaya
et al.
, 2012
Fig. 10
s883Tg + MO1-cacnb2a
cardiac ventricle sarcomere organization decreased process quality, abnormal
cell-cell adhesion mediated by cadherin decreased process quality, abnormal
Fig. 2
WT + MO1-cacnb2a
heart contraction decreased process quality, abnormal
heart decreased contractility, abnormal
heart edematous, abnormal
heart looping decreased process quality, abnormal
heart malformed, abnormal
Fig. 3
s883Tg + MO1-cacnb2a
, 
s883Tg + MO2-cacnb2a
heart looping decreased process quality, abnormal
heart malformed, abnormal
Fig. 4
s883Tg + MO1-cacnb2a
cardiac ventricle cardiac muscle cell circular, abnormal
cardiac ventricle cardiac muscle cell decreased area, abnormal
Fig. 5
WT + MO1-cacnb2a
blood circulation decreased process quality, abnormal
cardiac ventricle decreased volume, abnormal
heart contraction decreased rate, abnormal
Fig. 7
WT + MO1-cacnb2a
cardiac ventricle has fewer parts of type cardiac muscle cell, abnormal
Fig. 8
WT + MO1-cacnb2a
cell proliferation involved in heart morphogenesis decreased occurrence, abnormal
Fig. 9
f2Tg + MO1-cacnb2a
cell adhesion involved in heart morphogenesis decreased process quality, abnormal
heart tube increased fragility, abnormal
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