FIGURE

Fig. 4

ID

ZDB-FIG-120405-79

Publication

Chernyavskaya et al., 2012 - The voltage-gated calcium channel CACNB2 (β2.1) protein is required in the heart for control of cell proliferation and heart tube integrity

Other Figures

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Fig. 4

Cell morphology in wild-type and β2.1-depleted cardiomyocytes. A: Relative area of cells found in the outer curvature (OC) of the wild-type (n = 40) or β2.1-depleted hearts (n = 36) at 48 hours postfertilization (hpf). Asterisks denote the significant difference (P = 0.003). B: Tg(myl7:EGFP-HsHRAS) hearts were imaged as the basis for calculating cell area in OC cells. OC cells lie to the left of the red delineation. C: A magnified view of representative OC cells (from photos in B, rotated 90°) showing the elongated shape of wild-type cells compared with the rounder shape of β2.1-depleted cells.

Expression Data

Gene:	EGFP
Fish:	s883Tg s883Tg + MO1-cacnb2a
Knockdown Reagent:	MO1-cacnb2a
Anatomical Terms:	cardiac ventricle cardiac muscle cell ventricular myocardium plasma membrane
Stage:	Long-pec

Expression Detail

Antibody Labeling

Phenotype Data

Fish:	s883Tg + MO1-cacnb2a
Knockdown Reagent:	MO1-cacnb2a
Observed In:	cardiac ventricle cardiac muscle cell
Stage:	Long-pec

Phenotype Detail

Acknowledgments

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