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Phenotype Figure Summary
Marker:
dnm2a
Conditions:
Standard or Control
Publication
Data
Fish
Anatomy
Bragato
et al.
, 2016
Fig. 3
AB + MO3-dnm2a
, 
AB + MO4-dnm2a
skeletal muscle cell decreased amount, abnormal
skeletal muscle cell disorganized, abnormal
skeletal muscle cell increased diameter, abnormal
skeletal muscle cell morphology, abnormal
skeletal muscle cell nucleus increased amount, abnormal
skeletal muscle cell skeletal muscle myofibril disorganized, abnormal
somite hypoplastic, abnormal
somitogenesis disrupted, abnormal
Fig. 4
AB + MO3-dnm2a
, 
AB + MO4-dnm2a
skeletal muscle cell disorganized, abnormal
text only
AB + MO3-dnm2a
, 
AB + MO4-dnm2a
startle response decreased process quality, abnormal
thigmotaxis decreased process quality, abnormal
Gibbs
et al.
, 2013
Fig. 2
AB + MO2-dnm2a
eye decreased size, abnormal
pericardium edematous, abnormal
post-vent region curved, abnormal
somite shortened, abnormal
whole organism decreased length, abnormal
yolk edematous, abnormal
Fig. 4
AB + MO2-dnm2a
larval locomotory behavior decreased occurrence, abnormal
muscle disorganized, abnormal
somite decreased size, abnormal
thigmotaxis decreased functionality, abnormal
trunk musculature myofibril decreased size, abnormal
Koutsopoulos
et al.
, 2013
Fig. 3
s843Tg + MO1-dnm2a
, 
AB + MO1-dnm2a
intersegmental vessel increased branchiness, abnormal
intersegmental vessel sprouting angiogenesis process quality, abnormal
muscle cell development disrupted, abnormal
post-vent region myofibril disorganized, abnormal
Fig. S5
AB + MO1-dnm2a
post-vent region bent, abnormal
whole organism dead, abnormal
Li
et al.
, 2013
Fig. 2
WT + MO1-dnm2a
heart contraction process quality, abnormal
heart decreased functionality, abnormal
Fig. 7
WT + MO1-dnm2a
cardiac muscle cell chromatin located in cardiac muscle cell nuclear membrane, abnormal
cardiac muscle cell mitochondrion vacuolated, abnormal
heart apoptotic, abnormal
heart contraction process quality, abnormal
heart decreased functionality, abnormal
heart sarcolemma edematous, abnormal
heart Z disc blurry, abnormal
myocardium degenerate, abnormal
Kida
et al.
, 2007
Fig. 3
WT + MO1-dnm2a
notochord bent, abnormal
notochord decreased length, abnormal
somite condensed, abnormal
whole organism decreased length, abnormal
Fig. S9
WT + MO1-dnm2a
presumptive mesoderm decreased length, abnormal
somite condensed, abnormal
whole organism decreased length, abnormal
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