Genomic Feature
gl43
- ID
- ZDB-ALT-240104-4
- Name
- gl43
- Synonyms
- None
- Affected Genomic Region
- Construct
- None
- Type
- Allele with one deletion (1)
- Protocol
- embryos treated with
- Lab of Origin
- Lieschke Laboratory
- Current Source
- Other Pages
-
Notes
| Comment | Citation |
|---|---|
| This line contains to separate mutations. At the gRNA1 target site, there was a ... | Isiaku et al., 2024 |
Variants
- Variant Type
- Small Deletion
- Variant Location
- Chr 11: 29815424 - 29815443 (GRCz11) (1) Details
- Nucleotide change
- CATGCTCTCTCGTGGGCCAG/-
- Variant Notes
Effect on DNA/cDNA, transcript, protein (from publications)
- DNA/cDNA Change
- 20 bp deleted in Exon 3 (1)
- Transcript Consequence
- None
- Protein Consequence
- None
- Flanking Sequence
-
CGGATTTGTCAGGGTCACACTATGCATGGACTCAACATCTTGCCCCAAAGGAAGAATTTGCGCGCCAAATTATACGCATATGACCACAAGATGGCGACCACAGCCGAATTATATCGGTGGACGTTTCAAAATTGTTAATTTAACATTTGTATGAGTATTATGGCAGAAAAAAACGTTGTTTTATTACTAGACAGCTCACTGACAGATACAATTATCACAGGGTCTGACTAAGAAAATCTCATTTGTCTGATTTATCAACTAGCAAAGCACTTACAACGGCATCCCTTCGCCTGAGTGCTCGAATTCACTCACTTCTTTTCATTACTACCTTGAAGTGAACTATATTAGTGGACTCAAGTAAGGAATAGTGAATGAATGTCAATTTCGGATACAGCCCAAGTAGACAAACCTGTATAGATCCTCGGAGAAACGAGAGCAGATTTCTGCAGACCGGCAGCAGGATCAACATGCAGTTAAAGTTGAGACATGCAGCTGGAGCT
CATGCTCTCTCGTGGGCCAG/- CTGAGGAGGACAGAAAAACACAGGTGGGACTTTCATTTCCTATTTCCAGCTCCTATTTTCCAGCTTTATTCAACAATTTCACGCAAGACAAGTACTAAAAATTGTGTGTAGAGGAAAATATAAAAAATATGCTAAAATGTTGGTTAAATAAGAACTGCAGGACATTTTTTGAGATATAAATATGTATTTTTTTATTTAAATCGAGATAAATTTATTTTTAGGTTTTAACTTAAACGCTGCATTTTAAGAAATGGTCAGTCAAAATAATTACGGCATCACATTTACAACCAAAATGTAATTTTTGATTGTTAATGCTAAATATTAAAATAAGAATACAACATTGTGTATGTATAGCTGTACCAAAAATAATATTTTAATTTATTAGTGAAACAAAACCATGGTTAATTGAATTAATTATTTATTTGATTAATTATTCAATTATCGTTGCTAAATTTGCTAATTTCCATTAGGCAATTAAAATATTGGCCTTATAATTGCAT - Additional Sequence
- None
Fish
| Fish | Genomic Feature Zygosity | Parental Zygosity | Affected Genomic Regions | Phenotype | Gene Expression |
|---|---|---|---|---|---|
| cybbgl43/gl43 (TU) | Homozygous | ♀-/- ♂-/- | Fig. 3.  from Isiaku et al., 2024 | ||
| cybbgl43/+ (TU) | Heterozygous | ♀-/- ♂+/+ | Fig. 3. from Isiaku et al., 2024 | ||
| cybbgl43/gl43; c264Tg; gl28Tg (TU) | Complex | Fig. 4. from Isiaku et al., 2024 | |||
| cybbgl43/gl43; i114Tg (TU) | Complex | Fig. 2. from Isiaku et al., 2024 | |||
| cybbgl43/+; c264Tg; gl28Tg (TU) | Complex | Fig. 4. from Isiaku et al., 2024 |
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Supplemental Information
- Genotyping protocol
- None
- Isiaku, A.I., Zhang, Z., Pazhakh, V., Lieschke, G.J. (2024) A nox2/cybb zebrafish mutant with defective myeloid cell reactive oxygen species production displays normal initial neutrophil recruitment to sterile tail injuries. G3 (Bethesda). 14(6):
- Zebrafish Nomenclature Committee (2024) Nomenclature Data Curation (2024). Nomenclature Committee Submission.
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