Genomic Feature
uw39
- ID
- ZDB-ALT-160707-4
- Name
- uw39
- Synonyms
- None
- Affected Genomic Region
- Construct
- None
- Type
- Allele with one insertion (1)
- Protocol
- embryos treated with
- Lab of Origin
- Pelegri Lab
- Current Source
- Other Pages
Notes
No data available
Variants
- Variant Type
- Insertion
- Variant Location
- Chr 14: 41467380 - 41467381 (GRCz11) (1) Details
- Nucleotide change
- -/GA
- Variant Notes
- None
Effect on DNA/cDNA, transcript, protein (from publications)
- DNA/cDNA Change
- 2 bp inserted (1)
- Transcript Consequence
- Frameshift, Premature Stop (1)
- Protein Consequence
- None
- Flanking Sequence
-
CAGTTTTGGCCAAGAAACCCTTTTGATGGCAGGAGGGGAATCTCGAGACCTTTAGGTCCTTGCACTTTCCCAGTCCAACAATTCACGAACAGTCTATATTAGCGCTAAATGAGTCAATCCTATCGCAATAAGCTTCCCCCGCCGATTTCTCTCTTGTACCGATTCGTGAGGTGGTCAGCCTGAACTGTTAGTTTGGACAAGACAGAAAAGAGTCCGTGGAGGTGATAGTGGAACTGGCCCTCCAGATCTGGGCCCTCCTCGACAGCTTCTCCTTTCATCTGCGGCAGCTCTTCCTGCTTTACGGCCATTTCTAGAAAGCTGGCACCACCAGCCATCTCCCGCTTCAAAAGACCCCACTCCATGTCGTTCTTGATGGACTTGAGGAGCAGGTAGTGCTCGTACATGTCCCGCTGTTTGTTTGGGAAAGAGGGCTCGTTGTTGTTGTTGTTGTGGCTAACAGAAGCGTGGCTCTCCTGCTCTTCCAGAGGGACGTCTCGCAGA
-/GA AGGTTTGGCACCATGATGGTTTCGTCCATGTTGTTGGCTGCGGCGATGAACCGGTTCATGACATTGAGCAGCGAGTGCTTGTTGCAGTGGCTGTCGTTGCTGAGCTGCATCATGGCAAAGCTGCAATTGAAGCAAAAACAATCAGTTTGGATTAGTTTCACAACTGAGAGGCAGCAACTACTAAAATCAAAAGGAAGTTGTGGCATCACTTGGTTCCTGGACATGGCTCACATTCATGAGCTAAAACCTTGCAATACAGCCATCTGATGGCACATTAAGATTGAGGTAAAGCTGGTTTTATACATTACACATTTGCGTCGGAAAAATACTCCGTGCGAAAAGTAAAATAGTGAAATCATTAACAGCCTTTGACTATAAAAAGTACAACACTGTTCAGTCAAATAAATAGTGCTAATGTTGTTTTGAAGTCATACTTGCATGCGATTTTAGAGGGAATATTTAAAATACTATTGTAAAAACATGGGGATTATAAAACTAACT - Additional Sequence
- None
Fish
| Fish | Genomic Feature Zygosity | Parental Zygosity | Affected Genomic Regions | Phenotype | Gene Expression |
|---|---|---|---|---|---|
| mid1ip1luw39/uw39 | Homozygous | ♀+/- ♂+/- | Fig. S1 from Eno et al., 2016 | Fig. 10  from Eno et al., 2016 | |
| mid1ip1luw39 | Unknown | ♀-/- | Fig. S2 from Eno et al., 2018 | ||
| mid1ip1lt9792/+; mid1ip1luw39/+ | Complex | 2 figures from Eno et al., 2016 |
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Supplemental Information
- Genotyping protocol
- None
- Eno, C., Hansen, C.L., Pelegri, F. (2019) Aggregation, segregation and dispersal of homotypic germ plasm RNPs in the early zebrafish embryo. Developmental Dynamics : an official publication of the American Association of Anatomists. 248(4):306-318
- Eno, C., Pelegri, F. (2018) Modulation of F-actin dynamics by maternal mid1ip1L controls germ plasm aggregation and furrow recruitment in the zebrafish embryo. Development (Cambridge, England). 145(10)
- Eno, C., Solanki, B., Pelegri, F. (2016) aura/mid1ip1L regulates the cytoskeleton at the zebrafish egg-to-embryo transition. Development (Cambridge, England). 143(9):1585-99
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