Genomic Feature
zf586
- ID
- ZDB-ALT-151230-10
- Name
- zf586
- Synonyms
- None
- Affected Genomic Region
- Construct
- None
- Type
- Allele with one delins (1)
- Protocol
- embryos treated with
- Lab of Origin
- Current Source
- Other Pages
Notes
No data available
Variants
- Variant Type
- Delins
- Variant Location
- Chr 11: 23313879 - 23313881 (GRCz11) (1) Details
- Nucleotide change
- GAA/AAGTAATTCTAAGT
- Variant Notes
-
Tang et al (2015): 14-bp insertion and 3-bp deletion in exon 1
Effect on DNA/cDNA, transcript, protein (from publications)
- DNA/cDNA Change
- 14 bp inserted / 3 bp deleted in Exon 1 (1)
- Transcript Consequence
- None
- Protein Consequence
- None
- Flanking Sequence
-
CTTCTTGCTTTGAGGCAACAGTGCTAACCACTGAGCCATCATATTTATATATTTTTGTTATGAATAAAAATATAATATTGTTGATAAATAATTGATGTTAGTTCAGGTCTGTACACTCTCAGAAATAAAGGTACTGTACATGAGCTGTCACTGAGGTGGTACGTTTTCAAAAGGAACAAATTTGTACCTAAAATATTAATACCTTTATGGTACATATTAGTACCTAAACAGTACAAAAGTGTTCCTCTTTAAAATTTTAGATACTAATATATACTTTTGAGGTACCAATATGAACTCTTCACGTACAAATGTGTACCTTTTGTAAAGGTTCCGCCCCAGTGACAGCTCACGTACAGCTTTTTTTCTGAGAGTGTATACAACTGTGTTATTACATTTTGAAATAATTTCTTAAAGTATTGTTTATTTTGTATCAACTGAAATTAACAAATGGAACCTTATTTGTAAAGAATCATTAGTGAACTTACCTTCTAAGTAATACT
GAA/AAGTAATTCTAAGT AATGCCCAGAGGGGTTTGTGTGTACCCTCGCCACTGACAACATCAATATGACAGTAAGCAGCATCATTTTAATGTGTTTCAGAAAGAGAAGAGTTCTGAAAGAAAAGAACAAATGAAAATAAAAAATGATTAAAAATATGAAAAGTCTTTTGAATCATTAACACTTTTTAGTTTTGCTTATTTGATCACAAGATTCAGTGGTATTCATCCAGTTTTTCAGACTTATGAACTCACACGTGGCCCACACACATGCACACTTCAAAGAGAATTTAAGCTATCAAAAGCATCATAAATCAGCCTCTAACCTTTACTGCTGTGCTATTCTGTTCACATGCGTAAGAATAAAATGTATATAAAAAGAACAAGTATAATAATAAAAAATATAAAATACATTTTTTCTAAATACAAATAAAACAATGTTATACAGAATTCAACAGTTCCTTCTAAGAAATTATAATTCAGCAATAAAATTATATAAGAACATTTTCAGTTATTCATCA - Additional Sequence
- None
Fish
| Fish | Genomic Feature Zygosity | Parental Zygosity | Affected Genomic Regions | Phenotype | Gene Expression |
|---|---|---|---|---|---|
| kiss2zf587/zf587; kiss1zf586/zf586 | Complex | Fig. 1 from Tang et al., 2015 | |||
| kiss2zf587/zf587; gnrh3zf1051/zf1051; kiss1zf586/zf586 | Complex | Fig. 3 from Li et al., 2017 | |||
| kiss2zf587/zf587; gnrh3zf1051/zf1051; kiss1zf586/zf586 (AB) | Complex | Fig. 3 from Liu et al., 2017 | 2 figures from Liu et al., 2017 |
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Supplemental Information
- Genotyping protocol
- None
- Li, G., Tang, H., Chen, Y., Yin, Y., Ogawa, S., Liu, M., Guo, Y., Qi, X., Liu, Y., Parhar, I.S., Liu, X., Lin, H. (2017) Estrogen directly stimulates LHb expression at the pituitary level during puberty in female zebrafish. Molecular and Cellular Endocrinology. 461:1-11
- Liu, Y., Tang, H., Xie, R., Li, S., Liu, X., Lin, H., Zhang, Y., Cheng, C.H. (2017) Genetic Evidence for Multifactorial Control of the Reproductive Axis in Zebrafish. Endocrinology. 158:604-611
- Tang, H., Liu, Y., Luo, D., Ogawa, S., Yin, Y., Li, S., Zhang, Y., Hu, W., Parhar, I.S., Lin, H., Liu, X., Cheng, C.H. (2015) The kiss/kissr systems are dispensable for zebrafish reproduction: evidence from gene knockout studies. Endocrinology. 156(2):589-99
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