Gene
kiss1
- ID
- ZDB-GENE-080128-1
- Name
- KiSS-1 metastasis suppressor
- Symbol
- kiss1 Nomenclature History
- Previous Names
-
- kisspeptin (1)
- Type
- protein_coding_gene
- Location
- Chr: 11 Mapping Details/Browsers
- Description
- Enables kisspeptin receptor binding activity. Acts upstream of or within neuronal action potential and regulation of fear response. Predicted to be active in neuron projection. Is expressed in several structures, including brain; fat cell; liver; male organism; and pleuroperitoneal region. Human ortholog(s) of this gene implicated in hypogonadotropic hypogonadism 13 with or without anosmia. Orthologous to human KISS1 (KiSS-1 metastasis suppressor).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 32 figures from 21 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- 2 figures from Lupton et al., 2017
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| hypogonadotropic hypogonadism 13 with or without anosmia | Alliance | ?Hypogonadotropic hypogonadism 13 with or without anosmia | 614842 |
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Family | IPR020207 | Metastasis-suppressor KiSS-1 |
Domain Details Per Protein
| Protein | Length | Metastasis-suppressor KiSS-1 |
|---|---|---|
|
UniProtKB:A8C5J1
|
116 |
Interactions and Pathways
No data available
Plasmids
No data available