Gene

kiss1

ID
ZDB-GENE-080128-1
Name
KiSS-1 metastasis suppressor
Symbol
kiss1 Nomenclature History
Previous Names
  • kisspeptin (1)
Type
protein_coding_gene
Location
Chr: 11 Mapping Details/Browsers
Description
Enables G protein-coupled receptor binding activity. Involved in G protein-coupled receptor signaling pathway and positive regulation of cytosolic calcium ion concentration. Acts upstream of or within neuronal action potential and regulation of fear response. Is expressed in several structures, including brain; fat cell; liver; male organism; and pleuroperitoneal region. Human ortholog(s) of this gene implicated in hypogonadotropic hypogonadism 13 with or without anosmia. Orthologous to human KISS1 (KiSS-1 metastasis suppressor).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
25 figures from 17 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
2 figures from Lupton et al., 2017
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With kiss1 Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
hypogonadotropic hypogonadism 13 with or without anosmia Alliance ?Hypogonadotropic hypogonadism 13 with or without anosmia 614842
Associated With kiss1 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Family IPR020207 Metastasis-suppressor KiSS-1
Domain Details Per Protein
Protein Length Metastasis-suppressor KiSS-1
UniProtKB:A8C5J1 116
UniProtKB:B0F0Y7 116
UniProtKB:C6KIB1 116
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
Name Type Antigen Genes Isotype Host Organism Assay Source Citations
Ab1-kiss1 polyclonal Rabbit
  • IHC
2
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations