ZFIN ID: ZDB-EXP-151012-11
Experiment Conditions Description: amputation: caudal fin, chemical treatment: SB-202190
amputation: caudal fin
Name: amputation
Definition: Resection condtion in which all or part of an extremity such as the fin or tail are removed.
Ontology: Zebrafish Environment Condition Ontology [ZECO:0000172]
Name: caudal fin
Synonyms: tail, tail fin
Definition: Fin that is the most posterior median fin. It is composed of a complex of three modified centra and modified neural and hemal arches and spines.
Ontology: Anatomy Ontology [ZFA:0001058]
chemical treatment: SB-202190
Name: chemical treatment
Definition: Experimental condition in which the fish is treated with a chemical substance. This treatment could be administered by adding the chemical substance to the tank water, injections, or by consumption.
Ontology: Zebrafish Environment Condition Ontology [ZECO:0000111]
Name: SB-202190
Synonyms: 4-(4-fluorophenyl)-2-(4-hydroxyphenyl)-5-(4-pyridyl)imidazole, 4-[4-(4-fluorophenyl)-5-(pyridin-4-yl)-1H-imidazol-2-yl]phenol, SB 202190, SB202190
Definition: A member of the class of imidazoles that is 1H-imidazole in which the hydrogens at positions 2, 4, and 5 are replaced by 4-hydroxyphenyl, pyridin-4-yl, and 4-fluorophenyl groups, respectively. It is a widely used inhibitor of mitogen-activated protein kinase (MAPK) alpha and beta.
Ontology: Chebi [CHEBI:79090]
Publication: Ye et al., 2015