Search Ontology:
ChEBI

SB-202190

Term ID
CHEBI:79090
Synonyms
  • 4-(4-fluorophenyl)-2-(4-hydroxyphenyl)-5-(4-pyridyl)imidazole
  • 4-[4-(4-fluorophenyl)-5-(pyridin-4-yl)-1H-imidazol-2-yl]phenol
  • SB 202190
  • SB202190
Definition
A member of the class of imidazoles that is 1H-imidazole in which the hydrogens at positions 2, 4, and 5 are replaced by 4-hydroxyphenyl, pyridin-4-yl, and 4-fluorophenyl groups, respectively. It is a widely used inhibitor of mitogen-activated protein kinase (MAPK) α and β.
References
  • cas:152121-30-7
  • pubmed:11040446
  • pubmed:16183336
  • pubmed:18995898
  • pubmed:21853067
  • pubmed:22253611
  • pubmed:22986232
  • pubmed:24455679
  • pubmed:9632706
  • pubmed:9738669
  • reaxys:10467168
Ontology
ChEBI  ( EBI )
Relationships
Phenotype
Phenotype resulting from SB-202190
Phenotype where environments contain SB-202190
Phenotype modified by environments containing SB-202190
Phenotype affecting SB-202190
Human Disease Model