| ZFIN ID: ZDB-EXP-260310-22 |
Experiment Conditions Description: chemical treatment by environment: caspofungin, chemical treatment by environment: N-formyl-L-methionyl-L-leucyl-L-phenylalanine, fungal treatment by injection: Aspergillus fumigatus
| chemical treatment by environment: caspofungin |
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| Name: | chemical treatment by environment |
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| Synonyms: | |
| Definition: | Chemical treatment condition in which the chemical is introduced through the environment. For zebrafish this is the tank water. |
| Ontology: | Zebrafish Environment Condition Ontology [ZECO:0000238] |
| Name: | caspofungin |
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| Synonyms: | (10R,12S)-N-{(2R,6S,9S,11R,12S,14aS,15S,20S,23S,25aS)-12-[(2-aminoethyl)amino]-20-[(1R)-3-amino-1-hydroxypropyl]-23-[(1S,2S)-1,2-dihydroxy-2-(4-hydroxyphenyl)ethyl]-2,11,15-trihydroxy-6-[(1R)-1-hydroxyethyl]-5,8,14,19,22,25-hexaoxotetracosahydro-1H-dipyrr, (4R,5S)-5-((2-aminoethyl)amino)-N(2)-(10,12-dimethyltetradecanoyl)-4-hydroxy-L-ornithyl-L-threonyl-trans-4-hydroxy-L-prolyl-(S)-4-hydroxy-4-(p-hydroxyphenyl)-L-threonyl-threo-3-hydroxy-L-ornithyl-trans-3-hydroxy-L-proline cyclic (6-1)-peptide, 1-[(4R,5S)-5-[(2-aminoethyl)amino]-N(2)-(10,12-dimethyl-1-oxotetradecyl)-4-hydroxy-L-ornithine]-5-[(3R)-3-hydroxy-L-ornithine]-pneumocandin B0, caspofungin |
| Definition: | A semisynthetic cyclic hexapeptide echinocandin antibiotic which exerts its effect by inhibiting the synthesis of 1,3-β-D-glucan, an integral component of the fungal cell wall. |
| Ontology: | ChEBI [CHEBI:474180] ( EBI ) |
| chemical treatment by environment: N-formyl-L-methionyl-L-leucyl-L-phenylalanine |
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| Name: | chemical treatment by environment |
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| Synonyms: | |
| Definition: | Chemical treatment condition in which the chemical is introduced through the environment. For zebrafish this is the tank water. |
| Ontology: | Zebrafish Environment Condition Ontology [ZECO:0000238] |
| Name: | N-formyl-L-methionyl-L-leucyl-L-phenylalanine |
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| Synonyms: | F-Met-Leu-Phe, fMetLeuPhe, fMLF, fMLP, N-formyl-L-Met-L-Leu-L-Phe, N-formyl-L-methionyl-L-leucyl-L-phenylalanine, N-formyl-Met-Leu-Phe, N-formyl-Met-Leu-Phe-OH, N-formyl-methionyl-leucyl-phenylalanine, N-formylmethionine leucyl-phenylalanine |
| Definition: | A tripeptide composed of L-Met, L-Leu and L-Phe in a linear sequence with a formyl group at the amino terminus. It acts as a potent inducer of leucocyte chemotaxis and macrophage activator as well as a ligand for the FPR receptor. |
| Ontology: | ChEBI [CHEBI:53490] ( EBI ) |
| fungal treatment by injection: Aspergillus fumigatus |
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| Name: | fungal treatment by injection |
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| Synonyms: | |
| Definition: | Fungal treatment where the fungus is injected into the fish. |
| Ontology: | Zebrafish Environment Condition Ontology [ZECO:0000232] |
| Name: | Aspergillus fumigatus |
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| Synonyms: | Aspergillus fumigatus Fresen., 1863, Aspergillus fumigatus var. ellipticus, Aspergillus neoellipticus, Neosartorya fumigata, Sartorya fumigata |
| Definition: | |
| Ontology: | Taxonomy for ZECO [NCBITaxon:746128] |
| Publication: | Jones et al., 2019 |
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