N-formyl-L-methionyl-L-leucyl-L-phenylalanine

Term ID

CHEBI:53490

Synonyms

F-Met-Leu-Phe
fMetLeuPhe
fMLF
fMLP
N-formyl-L-Met-L-Leu-L-Phe
N-formyl-L-methionyl-L-leucyl-L-phenylalanine
N-formyl-Met-Leu-Phe
N-formyl-Met-Leu-Phe-OH
N-formyl-methionyl-leucyl-phenylalanine
N-formylmethionine leucyl-phenylalanine

Definition

A tripeptide composed of L-Met, L-Leu and L-Phe in a linear sequence with a formyl group at the amino terminus. It acts as a potent inducer of leucocyte chemotaxis and macrophage activator as well as a ligand for the FPR receptor.

References

beilstein:2315783
beilstein:8023425
cas:59880-97-6
kegg.compound:C11596
pubmed:16236365
pubmed:17907740
pubmed:18092743
pubmed:19067145
pubmed:19069235
pubmed:21126546
pubmed:21372136
pubmed:22484311
pubmed:23002436
pubmed:23109426
pubmed:23259992
pubmed:28711992
pubmed:29176405
pubmed:31033193
pubmed:34435345
pubmed:34572316
pubmed:35058789
wikipedia.en:N-Formylmethionine-leucyl-phenylalanine

Ontology

ChEBI ( EBI )

Resources

CTD

Relationships

Phenotype

Phenotype resulting from N-formyl-L-methionyl-L-leucyl-L-phenylalanine

Phenotype where environments contain N-formyl-L-methionyl-L-leucyl-L-phenylalanine

Phenotype modified by environments containing N-formyl-L-methionyl-L-leucyl-L-phenylalanine

Phenotype affecting N-formyl-L-methionyl-L-leucyl-L-phenylalanine

Human Disease Model